ID Q73JN0_TREDE Unreviewed; 540 AA.
AC Q73JN0;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=4-alpha-glucanotransferase {ECO:0000256|ARBA:ARBA00020295, ECO:0000256|RuleBase:RU361207};
DE EC=2.4.1.25 {ECO:0000256|ARBA:ARBA00012560, ECO:0000256|RuleBase:RU361207};
DE AltName: Full=Amylomaltase {ECO:0000256|ARBA:ARBA00031423, ECO:0000256|RuleBase:RU361207};
DE AltName: Full=Disproportionating enzyme {ECO:0000256|ARBA:ARBA00031501, ECO:0000256|RuleBase:RU361207};
GN Name=malQ {ECO:0000313|EMBL:AAS12905.1};
GN OrderedLocusNames=TDE_2387 {ECO:0000313|EMBL:AAS12905.1};
OS Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS / KCTC 15104).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS12905.1, ECO:0000313|Proteomes:UP000008212};
RN [1] {ECO:0000313|EMBL:AAS12905.1, ECO:0000313|Proteomes:UP000008212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104
RC {ECO:0000313|Proteomes:UP000008212};
RX PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A., Daugherty S.C.,
RA Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.,
RA Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S.,
RA Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E.,
RA Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT "Comparison of the genome of the oral pathogen Treponema denticola with
RT other spirochete genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC glucan.; EC=2.4.1.25; Evidence={ECO:0000256|ARBA:ARBA00000439,
CC ECO:0000256|RuleBase:RU361207};
CC -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC {ECO:0000256|ARBA:ARBA00005684, ECO:0000256|RuleBase:RU361207}.
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DR EMBL; AE017226; AAS12905.1; -; Genomic_DNA.
DR RefSeq; NP_972986.1; NC_002967.9.
DR RefSeq; WP_002680318.1; NC_002967.9.
DR AlphaFoldDB; Q73JN0; -.
DR STRING; 243275.TDE_2387; -.
DR CAZy; GH77; Glycoside Hydrolase Family 77.
DR PaxDb; 243275-TDE_2387; -.
DR GeneID; 2740689; -.
DR KEGG; tde:TDE_2387; -.
DR PATRIC; fig|243275.7.peg.2255; -.
DR eggNOG; COG1640; Bacteria.
DR HOGENOM; CLU_014132_1_0_12; -.
DR OrthoDB; 9811841at2; -.
DR Proteomes; UP000008212; Chromosome.
DR GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR003385; Glyco_hydro_77.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR NCBIfam; TIGR00217; malQ; 1.
DR PANTHER; PTHR32438; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR PANTHER; PTHR32438:SF5; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR Pfam; PF02446; Glyco_hydro_77; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361207};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU361207,
KW ECO:0000313|EMBL:AAS12905.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008212};
KW Transferase {ECO:0000256|RuleBase:RU361207, ECO:0000313|EMBL:AAS12905.1}.
SQ SEQUENCE 540 AA; 62847 MW; CEBB41BC644575A1 CRC64;
MKRSSGIILH PTSLPNDEGI GTIGKEAFAF IDWLKKTRTG VWQMLPIGPT GYGDSPYASF
SAFAGNPYLI SLQDLYEKGF LEKRDFTEYK KIVQENTDPK RADFGLIHYH KTKMLKKAAA
SLLHKMERDS SSKEELENFY QEESFWLDGY AAFMTIKEDY EERLDKENLV QGIWNEVWPK
ELALNKKDKI KEFLGKHSEE YETQKIIQFF FFSQWKKLKE YAEKNGIQLI GDIPIFAAMD
SADVWQNQSL FLLDKEATPK AVAGVPPDFF SPTGQLWGNP LYDWAKMKKD SYLWWKARIR
HTLKLFDIIR LDHFRGFEAF WAIPQGAKTA QEGKWVKGPD HHFFEEIQKD LISLDEKYRG
ELPILTEDLG VITPEVARLR DDFNFPTMKI LQFAFDLNEL KSENLTNPYL PHNHKKNCAV
YTGSHDNDTI MGWLEGSSDE MLKFIYTYLY GKKADKRICS ILNTYEFKKE LASEIIRKAF
SSVADFAAVQ MQDLLFLNSE ARMNAPSTVG KNWQWRVTGS YENCEMTEKL ELWNVLYNRV
//
