ID Q742B3_MYCPA Unreviewed; 302 AA.
AC Q742B3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
GN Name=galU {ECO:0000313|EMBL:AAS03241.1};
GN OrderedLocusNames=MAP_0924 {ECO:0000313|EMBL:AAS03241.1};
OS Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS (Mycobacterium paratuberculosis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=262316 {ECO:0000313|EMBL:AAS03241.1, ECO:0000313|Proteomes:UP000000580};
RN [1] {ECO:0000313|EMBL:AAS03241.1, ECO:0000313|Proteomes:UP000000580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-968 / K-10 {ECO:0000313|Proteomes:UP000000580};
RX PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA Kanjilal S., Kapur V.;
RT "The complete genome sequence of Mycobacterium avium subspecies
RT paratuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890}.
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DR EMBL; AE016958; AAS03241.1; -; Genomic_DNA.
DR RefSeq; WP_003877502.1; NZ_CP106873.1.
DR AlphaFoldDB; Q742B3; -.
DR STRING; 262316.MAP_0924; -.
DR GeneID; 75268903; -.
DR KEGG; mpa:MAP_0924; -.
DR eggNOG; COG1210; Bacteria.
DR HOGENOM; CLU_029499_1_0_11; -.
DR Proteomes; UP000000580; Chromosome.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000580}.
FT DOMAIN 12..277
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 302 AA; 32149 MW; 4E5D2B1AB572BAE7 CRC64;
MSCPNVVVPR TAIVPAAGLG TRFLPATKTV PKELLPVVDT PGIELVAAEA AEAGAERLVI
VTSEGKDGVV AHFVEDLVLE STLEERGKTA MLDKVRRAPR LIKVESVVQS EPLGLGHAIG
CVEPRLADDE DAVAVLLPDD LVLPTGVLGT MSKVRAHYGG TVLCAIEVTP EEISAYGVFD
VEPVPDDDPD VLRVKGMVEK PKAEDAPSMF AAAGRYVLDR AIFDALRRID RGAGGEVQLT
DGIALLISEG HPVHVVVHRG SRHDLGNPGG YLKAAVDFAL DRDDYGPDLR QWLVARLGLS
EQ
//
