ID Q749C6_GEOSL Unreviewed; 296 AA.
AC Q749C6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE SubName: Full=Helix-turn-helix transcriptional regulator, LysR family {ECO:0000313|EMBL:AAR36211.1};
GN OrderedLocusNames=GSU2817 {ECO:0000313|EMBL:AAR36211.1};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR36211.1, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR36211.1, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AE017180; AAR36211.1; -; Genomic_DNA.
DR RefSeq; NP_953861.1; NC_002939.5.
DR RefSeq; WP_010943443.1; NC_002939.5.
DR AlphaFoldDB; Q749C6; -.
DR SMR; Q749C6; -.
DR STRING; 243231.GSU2817; -.
DR DNASU; 2686872; -.
DR EnsemblBacteria; AAR36211; AAR36211; GSU2817.
DR KEGG; gsu:GSU2817; -.
DR PATRIC; fig|243231.5.peg.2840; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_1_7; -.
DR InParanoid; Q749C6; -.
DR OrthoDB; 5317428at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd08420; PBP2_CysL_like; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF39; RUBISCO TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 296 AA; 32368 MW; D700E17E0FA2D7D4 CRC64;
MAISLRQLEI FEKVAQCEHV TQASTQLFLT QSAVSMAIAE LERVAGAPLF ERRGKRLLLN
DRGRKILPEA EEVVRRTRAI EQFLEDSAGE PRGVLNVGAS TTIGNYILPE LIAEFSGNYP
DAKVLLTIGN AHQIEHALEK GELDLGLIEG IPHSGVLDST PWKKDELVVV VGKGHPWACD
GAASVEMLGN APWIMRETGS GTREVFEGAM AGKGISFSIS LELGHTEAIK KAIEAGLGVG
CLSRIAVNRE LEHGWLVEIA CPLDLKRTLS LQTRQSGYKT RLLCAFWSLL NRHKDI
//
