ID Q74BJ7_GEOSL Unreviewed; 762 AA.
AC Q74BJ7;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Sensor diguanylate cyclase/phosphodiesterase, GAF and PAS domain-containing {ECO:0000313|EMBL:AAR35420.1};
GN OrderedLocusNames=GSU2044 {ECO:0000313|EMBL:AAR35420.1};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR35420.1, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR35420.1, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
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DR EMBL; AE017180; AAR35420.1; -; Genomic_DNA.
DR RefSeq; NP_953093.1; NC_002939.5.
DR RefSeq; WP_010942687.1; NC_002939.5.
DR AlphaFoldDB; Q74BJ7; -.
DR SMR; Q74BJ7; -.
DR STRING; 243231.GSU2044; -.
DR EnsemblBacteria; AAR35420; AAR35420; GSU2044.
DR KEGG; gsu:GSU2044; -.
DR PATRIC; fig|243231.5.peg.2080; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_20_7; -.
DR InParanoid; Q74BJ7; -.
DR OrthoDB; 9777298at2; -.
DR Proteomes; UP000000577; Chromosome.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000577}.
FT DOMAIN 265..323
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 355..489
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 498..752
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 762 AA; 84972 MW; 9F939A4D599B764E CRC64;
MANLKRYNDG LFKLDLWIRR LLTIGESNEL YTALCDGVCD IVGAGTAVFT TIDMQAGTLT
YMAASGGWNA MVKGLAVPMK SGNLCASVAA CGTPLRIDQI SSRTDSCELL QVMDMDAAVL
VPVLEEGRVT ACLSAFRVGN PFDQIDEQLL QQYAHTASMV LRTVRLMVDL RHHAAMLEEE
NDERTRAEQK LAETNVFLNS VVDGVAEPMV VVGLDRRVIM TNRAARDFFQ ISDVGSDEAC
HRLIHHRDTP CVREEGMQCP LLDVRTAKRP VIATQEHRDR SGDKRVVEVM TSPLLGSDGV
AIGIIEAFRD ITDRRQAEET IRQMAYYDSL TGLPNRRLFN DRLRQSLALA QRNKRLLSVL
FLDLDRFKLI NDTLGHAVGD KLLMQVAKRL KGVCRRDGDT VARQGGDEFI INLSVISDVK
DALKVAQKII DSLRTPFVID GHELFITTSI GISVFPYDGR TSDALVKNAD FAMYRAKEQG
RNNCQLYTPE MNSKAFERLS LENNLRKGLE REELVLYYQP KVNVEDGQIS CMEALVRWQH
PTMGLVPPAR FIPLAEETGL IVPLGEWVLR TACRQNREWQ KAGYPPMQVA VNISPRQLQQ
GNLVDVVERA LSDSGLAPRW LVLEVTESIM MDGTESTLAT FRVLERMGIH IAIDDFGTGY
SSLHYLKKFP IHALKIDRSF IRDITTNPDD EAITSAVITM AKGLNLKVVA EGVETVEQLE
VLRALQCTHM QGHLFSRPAP AEQFAPVFGR AAGAYLGFGT WC
//
