ID Q74DR5_GEOSL Unreviewed; 469 AA.
AC Q74DR5;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=Sigma-54-dependent transcriptional response regulator {ECO:0000313|EMBL:AAR34626.1};
GN OrderedLocusNames=GSU1250 {ECO:0000313|EMBL:AAR34626.1};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR34626.1, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR34626.1, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
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DR EMBL; AE017180; AAR34626.1; -; Genomic_DNA.
DR RefSeq; NP_952303.1; NC_002939.5.
DR RefSeq; WP_010941905.1; NC_002939.5.
DR AlphaFoldDB; Q74DR5; -.
DR SMR; Q74DR5; -.
DR STRING; 243231.GSU1250; -.
DR EnsemblBacteria; AAR34626; AAR34626; GSU1250.
DR KEGG; gsu:GSU1250; -.
DR PATRIC; fig|243231.5.peg.1245; -.
DR eggNOG; COG2204; Bacteria.
DR HOGENOM; CLU_000445_0_6_7; -.
DR InParanoid; Q74DR5; -.
DR OrthoDB; 9814761at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071:SF13; RESPONSE REGULATOR HSFA; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..123
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 153..381
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT MOD_RES 58
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 469 AA; 51375 MW; A27C6717A5A59A45 CRC64;
MTTETAQTIV LVDDEENILK ASRLILLGNG FGNVVTLQDS RQLMPLLEQG GVAAVVLDLF
MPHLSGTELL PLIVERFPHI PAIVMTAVDE TETAVTCMKS GAFDYLVKPV ESGRLIASVT
KALEMGAMSR ELNSLKECLL DDRLDHPEAF ASIVTDSKKM RAVFQYLEVV SRSRQPILVT
GETGVGKELF ARAVHELSGV RGEFVAVNVA GLDDVMFSDT LFGHKKGAFT GADQARDGLI
ARAAGGTLFL DEIGDLNEAS QIKLLRLLQE KEYYPVGSDM ARKSEARIVC ATNRDLKKQI
EKEAFRNDLY YRLCAHQVQI PPLRERLEDL PLLIDYFLGE AAASLGRKKP TPPPELLTLL
SVYSFPGNVR ELQALIHDAV ARHGSGVLSL DSFRNIIGGD AVQLIPQTAV TSSDDPLSAI
FGRFPTVREV EDYLMAEAMK RARGNQGIAA TMLGITRQTL NKRLQAKKG
//
