ID Q74KX6_LACJO Unreviewed; 255 AA.
AC Q74KX6;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE SubName: Full=Two-component system response regulator {ECO:0000313|EMBL:AAS08440.1};
GN OrderedLocusNames=LJ_0449 {ECO:0000313|EMBL:AAS08440.1};
OS Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=257314 {ECO:0000313|EMBL:AAS08440.1, ECO:0000313|Proteomes:UP000000581};
RN [1] {ECO:0000313|EMBL:AAS08440.1, ECO:0000313|Proteomes:UP000000581}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNCM I-1225 / La1 / NCC 533
RC {ECO:0000313|Proteomes:UP000000581};
RX PubMed=14983040; DOI=10.1073/pnas.0307327101;
RA Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C.,
RA Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R.,
RA Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.;
RT "The genome sequence of the probiotic intestinal bacterium Lactobacillus
RT johnsonii NCC 533.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004).
CC -!- FUNCTION: Required for high-level post-exponential phase expression of
CC a series of secreted proteins. {ECO:0000256|ARBA:ARBA00037164}.
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DR EMBL; AE017198; AAS08440.1; -; Genomic_DNA.
DR RefSeq; WP_011161590.1; NC_005362.1.
DR AlphaFoldDB; Q74KX6; -.
DR KEGG; ljo:LJ_0449; -.
DR PATRIC; fig|257314.6.peg.475; -.
DR eggNOG; COG3279; Bacteria.
DR HOGENOM; CLU_000445_14_6_9; -.
DR Proteomes; UP000000581; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.40.50.1020; LytTr DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR046947; LytR-like.
DR InterPro; IPR007492; LytTR_DNA-bd_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR37299:SF3; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1.
DR PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF04397; LytTR; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00850; LytTR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50930; HTH_LYTTR; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT DOMAIN 5..135
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 153..254
FT /note="HTH LytTR-type"
FT /evidence="ECO:0000259|PROSITE:PS50930"
FT MOD_RES 66
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 255 AA; 29978 MW; B3774906E292BD96 CRC64;
MRTFKIAICE DDRDQNEHIN YMIKKSCIFL SSEHQKFEIS NTFYSYESIF QFINSSSKLP
DIYFLDIQLS SKPDDKNGIE LANLIRNKQK TAQIIFITTH DELALLTFEY QIEALDYIVK
SNEEAKIQTK ITQDLEKSAY KLEEFLEKKN NIFTYQIGNN FYRVNTDDIY YISTTPFPHR
LKIIAKNEIS EFTGDIKNIQ DKIPGFIKVS QSYLVNMKNI TSINLKKRLI LFPTGEEIQF
AFSAKRKIKE YLMAD
//
