ID Q75QC4_RAT Unreviewed; 508 AA.
AC Q75QC4;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 08-NOV-2023, entry version 90.
DE SubName: Full=BS69-delta {ECO:0000313|EMBL:BAD11086.1};
GN Name=Zmynd11 {ECO:0000313|RGD:1303252};
GN Synonyms=BS69 {ECO:0000313|EMBL:BAD11086.1};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|EMBL:BAD11086.1};
RN [1] {ECO:0000313|EMBL:BAD11086.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Liver {ECO:0000313|EMBL:BAD11086.1};
RA Ogata-Kawata H., Yamada K., Uesaka-Yoshino M., Miyamoto K.;
RT "BS69, a corepressor interacting with ZHX1, is a bifunctional transcription
RT factor.";
RL Front. Biosci. 12:1911-1926(2007).
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DR EMBL; AB162620; BAD11086.1; -; mRNA.
DR RefSeq; NP_976244.2; NM_203368.2.
DR AlphaFoldDB; Q75QC4; -.
DR GeneID; 291259; -.
DR AGR; RGD:1303252; -.
DR CTD; 10771; -.
DR RGD; 1303252; Zmynd11.
DR OrthoDB; 764287at2759; -.
DR Genevisible; Q75QC4; RN.
DR GO; GO:0005634; C:nucleus; ISO:RGD.
DR GO; GO:0003690; F:double-stranded DNA binding; ISO:RGD.
DR GO; GO:0042393; F:histone binding; ISO:RGD.
DR GO; GO:0035064; F:methylated histone binding; ISO:RGD.
DR GO; GO:0003714; F:transcription corepressor activity; ISO:RGD.
DR GO; GO:0008270; F:zinc ion binding; ISO:RGD.
DR GO; GO:0051607; P:defense response to virus; ISO:RGD.
DR GO; GO:0043124; P:negative regulation of canonical NF-kappaB signal transduction; ISO:RGD.
DR GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; ISO:RGD.
DR GO; GO:0046329; P:negative regulation of JNK cascade; ISO:RGD.
DR GO; GO:0009966; P:regulation of signal transduction; IBA:GO_Central.
DR GO; GO:0034243; P:regulation of transcription elongation by RNA polymerase II; ISO:RGD.
DR CDD; cd05492; Bromo_ZMYND11; 1.
DR CDD; cd20159; PWWP_BS69; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR047268; PWWP_BS69.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR047269; ZMY11.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR46379; ZINC FINGER MYND DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR46379:SF1; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 2: Evidence at transcript level;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 92..144
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 186..237
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 469..504
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 272..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 393..466
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 296..321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 59547 MW; E2786295E1C0C2D4 CRC64;
MSRVHGMHPK ETTRQLSLAV KDGLIVETLT VGCKGSKAGI EQEGYWLPGD EISIKKKHSN
KQEMGTYLRF IVSRMKERAI DLNKKGKDSK HPMYRRLVHS AVDVPTIQEK VNEGKYRSYE
EFKADAQLLL HNTVIFYGAD SEQADIARML YKDTCHELDE LQLCKNCFYL SNARPDNWFC
YPCIPNHELV WAKMKGFGFW PAKVMQKEDN QVDVRFFGHH HQRAWIPSEN IQDITVNVHR
LHVKRSMGWK KACDELELHQ RFLREGRFWK SKNEDRGEEE AESSISSTSN EQLKATQEPR
AKKGRRNQSV EPKKEEPEPE TEAVSSSQEI PTMPQPIERV SVSTQTKKLS ASSPRMLHRS
TQTASDGVCQ SMCHDKYTKI FNDFKDRMKS DHKRETERVV REALEKLRSE MEEEKRQAVN
KAVANMQGEM DRKCKQVKEK CKEEFVEEIK KLAAQHKQLI SQTKKKQWCY NCEEEAMYHC
CWNTSYCSIK CQQEHWHAEH KRTCRRKR
//
