ID Q75VL8_VIBVL Unreviewed; 471 AA.
AC Q75VL8;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 24-JAN-2024, entry version 86.
DE SubName: Full=Cytolysin {ECO:0000313|EMBL:BAC99982.1, ECO:0000313|EMBL:POB50157.1};
GN Name=vvhA {ECO:0000313|EMBL:BAC99982.1};
GN ORFNames=CRN52_00080 {ECO:0000313|EMBL:POB50157.1};
OS Vibrio vulnificus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=672 {ECO:0000313|EMBL:BAC99982.1};
RN [1] {ECO:0000313|EMBL:BAC99982.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=L-180 {ECO:0000313|EMBL:BAC99982.1};
RX PubMed=15965298;
RA Senoh M., Miyoshi S., Okamoto K., Fouz B., Amaro C., Shinoda S.;
RT "The cytotoxin-hemolysin genes of human and eel pathogenic Vibrio
RT vulnificus strains: comparison of nucleotide sequences and application to
RT the genetic grouping.";
RL Microbiol. Immunol. 49:513-519(2005).
RN [2] {ECO:0000313|EMBL:POB50157.1, ECO:0000313|Proteomes:UP000237466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT4608 {ECO:0000313|EMBL:POB50157.1,
RC ECO:0000313|Proteomes:UP000237466};
RX PubMed=29358930;
RA Roig F.J., Gonzalez-Candelas F., Sanjuan E., Fouz B., Feil E.J.,
RA Llorens C., Baker-Austin C., Oliver J.D., Danin-Poleg Y., Gibas C.J.,
RA Kashi Y., Gulig P.A., Morrison S.S., Amaro C.;
RT "Phylogeny of Vibrio vulnificus from the Analysis of the Core-Genome:
RT Implications for Intra-Species Taxonomy.";
RL Front. Microbiol. 8:2613-2613(2018).
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DR EMBL; AB124802; BAC99982.1; -; Genomic_DNA.
DR EMBL; PDGH01000005; POB50157.1; -; Genomic_DNA.
DR RefSeq; WP_011152263.1; NZ_WRPB01000001.1.
DR AlphaFoldDB; Q75VL8; -.
DR SMR; Q75VL8; -.
DR CAZy; CBM13; Carbohydrate-Binding Module Family 13.
DR GeneID; 66967392; -.
DR KEGG; vvl:VV93_v1c39010; -.
DR PATRIC; fig|672.127.peg.2990; -.
DR OMA; HVAFYLN; -.
DR Proteomes; UP000237466; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0051715; P:cytolysis in another organism; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.70.240.10; Leukocidin/porin MspA; 2.
DR InterPro; IPR016183; Leukocidin/Hemolysin_toxin.
DR InterPro; IPR036435; Leukocidin/porin_MspA_sf.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR Pfam; PF07968; Leukocidin; 1.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56959; Leukocidin-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..471
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014587588"
FT DOMAIN 338..465
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
SQ SEQUENCE 471 AA; 52872 MW; F5F41B5055BCB40A CRC64;
MKKMTLFTLS LLATAVQVGA QEYVPIVEKP IYITSSKIKC VLHTSGDFNA TRDWCNAGAS
IDVRVNVAQM RSVQSATSDG FTPDAKIVRF TVDADKPGTG IHLVNELQQD HSWFQSWANR
RTYIGPFASS YDLWVKPVSG YTPKKARDLP QNENKNYQHR DTYGYSIGIN GKVGAEVNKD
GPKVGGEVSG SFTYNYSKTL VFDTKDYRIN NRSSLSDFDI SFEREFGECD ELRRQELGCY
FTAAHWGSGW VFDKTKFNPI SYSNFKPNYD VLYEAPVSET GVTDFEMGVK LNYRARFGTV
LPSALFSVYG SAGSSTNSST VKQRIRIDWN HPLFEAEAHV TLQSLSNNDL CLDVYGENGD
KTVAGGSVNG WSCHGSWNQV WGLDKEERYR SRVASDRCLT VNADKTLTVE QCGANLAQKW
YWEGDKLISR YVDGSNTRYL LNIVGGRNVQ VTPENEANQA RWKPTLQQVK L
//
