ID Q7MTJ6_PORGI Unreviewed; 431 AA.
AC Q7MTJ6;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=4-hydroxybutyrate CoA-transferase {ECO:0000313|EMBL:AAQ66936.1};
GN Name=abfT-2 {ECO:0000313|EMBL:AAQ66936.1};
GN OrderedLocusNames=PG_1956 {ECO:0000313|EMBL:AAQ66936.1};
OS Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=242619 {ECO:0000313|EMBL:AAQ66936.1, ECO:0000313|Proteomes:UP000000588};
RN [1] {ECO:0000313|EMBL:AAQ66936.1, ECO:0000313|Proteomes:UP000000588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-308 / W83 {ECO:0000313|Proteomes:UP000000588};
RX PubMed=12949112; DOI=10.1128/JB.185.18.5591-5601.2003;
RA Nelson K., Fleishmann R., DeBoy R., Paulsen I., Fouts D., Eisen J.,
RA Daugherty S., Dodson R., Durkin A., Gwinn M., Haft D., Kolonay J.,
RA Nelson W., White O., Mason T., Tallon L., Gray J., Granger D., Tettelin H.,
RA Dong H., Galvin J., Duncan M., Dewhirst F., Fraser C.;
RT "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT gingivalis strain W83.";
RL J. Bacteriol. 185:5591-5601(2003).
RN [2] {ECO:0007829|PDB:3D3U}
RP X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 1-191 AND 193-431.
RA Forouhar F., Neely H., Zhang X.-Z., Price II W.N., Hussain M.,
RA Seetharaman J., Xiao R., Conover K., Cunningham K., Ma L.-C., Ho C.K.,
RA Everett J.K., Acton T.B., Montelione G.T., Hunt J.F., Tong L.;
RT "Crystal structure of 4-hydroxybutyrate CoA-transferase (abfT-2) from
RT Porphyromonas gingivalis.";
RL Submitted (MAY-2008) to the PDB data bank.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; AE015924; AAQ66936.1; -; Genomic_DNA.
DR RefSeq; WP_005874820.1; NC_002950.2.
DR PDB; 3D3U; X-ray; 2.80 A; A=1-191, A=193-431.
DR PDBsum; 3D3U; -.
DR AlphaFoldDB; Q7MTJ6; -.
DR SMR; Q7MTJ6; -.
DR STRING; 242619.PG_1956; -.
DR EnsemblBacteria; AAQ66936; AAQ66936; PG_1956.
DR KEGG; pgi:PG_1956; -.
DR PATRIC; fig|242619.8.peg.1811; -.
DR eggNOG; COG0427; Bacteria.
DR HOGENOM; CLU_030703_1_0_10; -.
DR BioCyc; PGIN242619:G1G02-1828-MONOMER; -.
DR EvolutionaryTrace; Q7MTJ6; -.
DR Proteomes; UP000000588; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR21432:SF20; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR21432; ACETYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3D3U};
KW Reference proteome {ECO:0000313|Proteomes:UP000000588};
KW Transferase {ECO:0000313|EMBL:AAQ66936.1}.
FT DOMAIN 5..188
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 273..425
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 431 AA; 47761 MW; 73BFC73C5566F260 CRC64;
MQWQELYRQR VCSADEAVVD SLKPGTKVVF GHAAAAPVRF SQAMYRQREK LENITVFHML
YFGDAPHLAP EMRSHVHPTL NFLEGNSRPA SRDRRVDFIP CHFHEVPELF RQGFFPLDVA
VVQVSTPNEE GYCSFGVSCD YTKAAAECAP VVVAEVNKQM PFIGGENLIH ISKLTHIIEV
DEPIAEVLPP AISDLELRIG QNCASLIKDG DTLQLGIGGI PDAVLRALEG HKDLGIHTEM
FTDGVMRMIR KGIINGKKKT LHPEKVVTSL IFGSKELYDF VNNNPVIECY PVDYINNPDV
IGKNDRMVSI NSCLEMDLMG QAASESIGYE QFSGSGGQVD FLRGAKRSKG GISIMAFPST
AKKGTESRIV PILKEGACVT TGRNEVDYVV TEYGVARLRG ATLRQRAEAL TAIAHPDFRP
ALEEEIRRRF E
//
