ID Q7Q285_ANOGA Unreviewed; 574 AA.
AC Q7Q285;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 3.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=AGAP003980-PA {ECO:0000313|EMBL:EAA13587.3};
GN Name=1278798 {ECO:0000313|EnsemblMetazoa:AGAP003980-PA};
GN ORFNames=AgaP_AGAP003980 {ECO:0000313|EMBL:EAA13587.3};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA13587.3};
RN [1] {ECO:0000313|EMBL:EAA13587.3, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA13587.3,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA13587.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA13587.3};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA13587.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA13587.3};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA13587.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA13587.3};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA13587.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA13587.3};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP003980-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP003980-PA};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
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DR EMBL; AAAB01008978; EAA13587.3; -; Genomic_DNA.
DR RefSeq; XP_318430.3; XM_318430.5.
DR AlphaFoldDB; Q7Q285; -.
DR STRING; 7165.Q7Q285; -.
DR PaxDb; 7165-AGAP003980-PA; -.
DR EnsemblMetazoa; AGAP003980-RA; AGAP003980-PA; AGAP003980.
DR GeneID; 1278798; -.
DR KEGG; aga:AgaP_AGAP003980; -.
DR VEuPathDB; VectorBase:AGAP003980; -.
DR eggNOG; KOG1299; Eukaryota.
DR HOGENOM; CLU_013933_3_1_1; -.
DR InParanoid; Q7Q285; -.
DR OMA; VHQLNNA; -.
DR OrthoDB; 49088at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 1.25.40.60; -; 1.
DR Gene3D; 3.40.50.1910; -; 1.
DR Gene3D; 3.40.50.2060; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR PANTHER; PTHR11679:SF3; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF00995; Sec1; 1.
DR PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007062}.
SQ SEQUENCE 574 AA; 65167 MW; AFDE85383EE34BF2 CRC64;
MNVIRAIQTY IDKMITDAGP GMKILMMDRE TISIVSMAFA QSEMLQKEVF LFERLDSVRS
NEKLKYLKCI VFIRPTKDNI FMLQQELQSP KFGSYYIYFS NIIPRTDIKI LAESDEGESV
QDFKEIYADY LPVNPNLFSL HIPTCLQALS WNPEALERST QGLVSVLLSF KFRPAIRYRA
GSTAAQTLAK KVHETINKET ALFSFRPPED GAAPPLLLIL DRRDDPITPL LNQWTYQAMV
HELLSINKQR VDLSRVAGVP KDLKEVVLST EQDEFYANNL YANFGEIATT IKVLMDEFQK
KANDQRKIES IADMKNFVET YPQFRKMSGT VTKHLVLISE LSVQVGQQQL FEVSELEQEI
ACRADHSTQL QRVKRLVSEG KISAANALRL VLLYAMRYER HANCDTSGLL KLLQDRGGRS
HIVPRMLEYI STVARQELFN TVKITDAVKL TRNLIKELKG VENVYAQHEC VLKGTLEEVI
KGRPLDAQYP IMGNEVPFRR PPAEVIVFIV GGATYEEALA VHRYNQEGYR IVLGGTTIHN
SESFIEEVLA ATTGVPFKHS RSLQQFHHAP AGTA
//
