ID Q7QCJ3_ANOGA Unreviewed; 763 AA.
AC Q7QCJ3;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 3.
DT 27-MAR-2024, entry version 125.
DE SubName: Full=AGAP002655-PA {ECO:0000313|EMBL:EAA08034.3};
GN Name=1273304 {ECO:0000313|EnsemblMetazoa:AGAP002655-PA};
GN ORFNames=AgaP_AGAP002655 {ECO:0000313|EMBL:EAA08034.3};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA08034.3};
RN [1] {ECO:0000313|EMBL:EAA08034.3, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA08034.3,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA08034.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA08034.3};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA08034.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA08034.3};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA08034.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA08034.3};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA08034.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA08034.3};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP002655-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP002655-PA};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAAB01008859; EAA08034.3; -; Genomic_DNA.
DR RefSeq; XP_312269.3; XM_312269.5.
DR AlphaFoldDB; Q7QCJ3; -.
DR STRING; 7165.Q7QCJ3; -.
DR PaxDb; 7165-AGAP002655-PA; -.
DR EnsemblMetazoa; AGAP002655-RA; AGAP002655-PA; AGAP002655.
DR GeneID; 1273304; -.
DR KEGG; aga:AgaP_AGAP002655; -.
DR VEuPathDB; VectorBase:AGAP002655; -.
DR eggNOG; KOG0123; Eukaryota.
DR HOGENOM; CLU_411771_0_0_1; -.
DR InParanoid; Q7QCJ3; -.
DR OMA; HVFPGRK; -.
DR OrthoDB; 5477987at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR CDD; cd00590; RRM_SF; 4.
DR Gene3D; 3.30.70.330; -; 5.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR24012:SF885; EG:132E8.1 PROTEIN-RELATED; 1.
DR PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 5.
DR SMART; SM00360; RRM; 6.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 5.
DR PROSITE; PS50102; RRM; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007062};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 14..82
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 94..174
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 173..257
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 265..347
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 383..466
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 474..541
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 659..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..763
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 763 AA; 85351 MW; 69C3797CA342E588 CRC64;
MADNPSRMKA DNKKKLNVGN LPADITEEEL RELFADHPVE SVEIFHYKQY TLALLLFKDK
ETATKALKEK ENSVFRGRRL RMHLEFIVIC HMKKDVFVHV VDNENVTEED VYEKFKDLAK
VQSVVLFHPL AYVTCTSPED KEEAMKKIVE AGINVYDCNG HDQNQHIDVL RAAKLFFRNL
NRVQMYNIPE SWISSQDELK KAVESSGTVT EVRVTTGNFG PAAQVFYETA DEAKAAAEKL
NQQLFEGKRV HAHHVIATMI PNFKTSVYVE NLDKTITEEM LYAHFEQYGE IDFVNRRKFG
DEHGMVCFKE ASSVDRALEC TTLPVTKKEG EETTTEDKTI VVKRYDGPLV LDIKLPAMKK
GASSEEGEEQ KQRPPPQPLA KLWPIYVANL PYKADKREIK QYFSSYGGHI KFIFSPNIPS
YKQSQTSMVM AALIYFARRE QANEAIKAFN GKHFQSKCLH VFPGRKDTYF DVEKSIKVVR
LNLAVTEEKL FEKFRKFGFI ECVVKKDRTT AYIEFRDKEI AEKVLKLDEK QRPVRCNVEA
VTGKINKKIF KENDEKISLA MQEIIDKNPA VLENVSSDRS SGPPPLKRSR FSGPANFGMQ
GPRNQFNPNN GGDFSNPQVI QDLLRLAFIS GKNLGEGLAI SGNSNPFNSG DPPLPNLNLT
NGFGGGNQRN SFNNSNNGNF GGSSNNASGN MGGGNRNNMG GGGVNRNFGQ NVGGGGGAMG
SGGYGRVNMG GGFGGKRFNG GSQQTNRMGQ NNRQGGGNQN RRF
//
