ID Q7QH55_ANOGA Unreviewed; 726 AA.
AC Q7QH55;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 5.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=AGAP004080-PA {ECO:0000313|EMBL:EAA05369.5};
GN Name=1270879 {ECO:0000313|EnsemblMetazoa:AGAP004080-PA};
GN ORFNames=AgaP_AGAP004080 {ECO:0000313|EMBL:EAA05369.5};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA05369.5};
RN [1] {ECO:0000313|EMBL:EAA05369.5, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA05369.5,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA05369.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA05369.5};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA05369.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA05369.5};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA05369.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA05369.5};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA05369.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA05369.5};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP004080-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP004080-PA};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
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DR EMBL; AAAB01008817; EAA05369.5; -; Genomic_DNA.
DR RefSeq; XP_309632.5; XM_309632.5.
DR AlphaFoldDB; Q7QH55; -.
DR STRING; 7165.Q7QH55; -.
DR PaxDb; 7165-AGAP004080-PA; -.
DR EnsemblMetazoa; AGAP004080-RA; AGAP004080-PA; AGAP004080.
DR GeneID; 1270879; -.
DR KEGG; aga:AgaP_AGAP004080; -.
DR VEuPathDB; VectorBase:AGAP004080; -.
DR eggNOG; KOG3759; Eukaryota.
DR HOGENOM; CLU_020366_0_0_1; -.
DR InParanoid; Q7QH55; -.
DR OMA; WSYVART; -.
DR OrthoDB; 2910740at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR CDD; cd17683; RUN_RUNDC1; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047343; RUSC1_2.
DR PANTHER; PTHR15591; RUN AND SH3 DOMAIN CONTAINING; 1.
DR PANTHER; PTHR15591:SF19; RUN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT DOMAIN 457..714
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 304..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 82631 MW; 31C9D94DD7933DB1 CRC64;
MSVNIRIDEA RSLGDQHDQQ GCDGQTTCEE ACRDDGDVEV DMKFGLFVDT DRSMPRNVSE
EEFDFDSAFS SESNQGLTDE STIDHLDDRM LPDGAVERER LKSLEDEHEI LSSNLIALTS
HFAQVQLRLR QIVEAPPQER DTLLKNLEEF AFLGIPEIQQ NPVKQNIPEI VANLDKSPES
VENLREKQQE LIGQLKSQLM DLERYAYESG AGILPQTILL EKQKVIIEEI KKKINLNLNE
LDLPQLTSED LRQQVDSALD ELVNPLKMKE QLVTQLKTQI QDLERFISFL QTNEKAEIKK
RFLEQQKQQE QRAEASKGNE GRSQHSSDRH TLSKPMSAHP SNGTSASQAA AKRESFNSKA
FGLMDKAGTL LQMFALSQFN CGSEHRNSET NYQSKMMTRT RQNCWGDIRA RLEYDVQEIA
SLALTMQNEI SPKEADHNDE EDEDSNRPGR DNRKNYELTL LVRKRLAKTI QRLMQHGLRS
ISESASHSLV PFISGCFSTT GSGHSGTNHS SMSGRANESF YRSEVRRKST GATTTAPKKQ
SSYVEEDTSN AAVTEENLFS QLDDDEEEDM EPQFDSNNKD EMHVWELLLV YYNIKNGDRY
NSTPARKLSE SFNLDIVDGR PLSNKQSLLS AIGSIIALHS PYKRSYDSQF KAFVCAGLNA
QKLTQWLYLI FQCKELVSSH YASWSYVANT GFRDALKTLD CLTQYRFDLP VDLSIRQFKN
IKDVFM
//
