ID Q7RFG7_PLAYO Unreviewed; 4507 AA.
AC Q7RFG7;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=1 beta dynein heavy chain {ECO:0000313|EMBL:EAA16641.1};
GN ORFNames=PY04739 {ECO:0000313|EMBL:EAA16641.1};
OS Plasmodium yoelii yoelii.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=73239 {ECO:0000313|EMBL:EAA16641.1, ECO:0000313|Proteomes:UP000008553};
RN [1] {ECO:0000313|EMBL:EAA16641.1, ECO:0000313|Proteomes:UP000008553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17XNL {ECO:0000313|EMBL:EAA16641.1,
RC ECO:0000313|Proteomes:UP000008553};
RX PubMed=12368865; DOI=10.1038/nature01099;
RA Carlton J.M., Angiuoli S.V., Suh B.B., Kooij T.W., Pertea M., Silva J.C.,
RA Ermolaeva M.D., Allen J.E., Selengut J.D., Koo H.L., Peterson J.D., Pop M.,
RA Kosack D.S., Shumway M.F., Bidwell S.L., Shallom S.J., van Aken S.E.,
RA Riedmuller S.B., Feldblyum T.V., Cho J.K., Quackenbush J., Sedegah M.,
RA Shoaibi A., Cummings L.M., Florens L., Yates J.R., Raine J.D., Sinden R.E.,
RA Harris M.A., Cunningham D.A., Preiser P.R., Bergman L.W., Vaidya A.B.,
RA van Lin L.H., Janse C.J., Waters A.P., Smith H.O., White O.R.,
RA Salzberg S.L., Venter J.C., Fraser C.M., Hoffman S.L., Gardner M.J.,
RA Carucci D.J.;
RT "Genome sequence and comparative analysis of the model rodent malaria
RT parasite Plasmodium yoelii yoelii.";
RL Nature 419:512-519(2002).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA16641.1}.
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DR EMBL; AABL01001455; EAA16641.1; -; Genomic_DNA.
DR STRING; 73239.Q7RFG7; -.
DR PaxDb; 73239-Q7RFG7; -.
DR EnsemblProtists; EAA16641; EAA16641; EAA16641.
DR InParanoid; Q7RFG7; -.
DR OMA; NFEYILR; -.
DR Proteomes; UP000008553; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 7.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF183; DYNEIN AXONEMAL HEAVY CHAIN 2; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 2.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008553}.
FT DOMAIN 362..484
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 651..864
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1175..1292
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 1798..1881
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2652..2976
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 4053..4191
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 4229..4503
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT REGION 304..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3446..3645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2636..2748
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2863..2904
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 3456..3481
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3489..3534
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3535..3553
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3554..3580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3605..3619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3620..3645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAA16641.1"
SQ SEQUENCE 4507 AA; 530483 MW; F84BCB47F4580664 CRC64;
DNFLWLCXIK YILTEDLENT YLASQKGLSR SDMSDQHGNM LIDNQTKNNS KINNIKNELD
RDLINGKYMN RKESTDPITS STVYSVAKKN NEDLSFNKKL SNTKHDAFFR KDTTRKAEIS
NANKNIKEDK KNVIGNNNNS QAKKINFAGK NSSKILNGKG KGNICCKTEG VNVTKKKEKG
SKNNEENDQY IDILEKEYIK IDETEREDEE EEVYECEEAN EVESQKNFDL DKLEDDENEE
TEKNVNYLEI NENDDNLNEG RNNYKNNYFD KNKIDELEEG KDNFSENAEV KGNKTLIKNK
RALSDKKISD NNNDGNRKEM NKIEEDVDDK NSKQLKYLKT INLMLKKSMT LYLHYFNNKR
KYSYEYQGNS SRLVITPLTE KCFYSCLFSL DNFYVNAIKG ETGVGKSETI KEFSKMFGTN
IISINCNNNN TSKYIGNILS GLLQSGFWCC FDEFNRIEGN VIAVIVEQFR SIKHILHRLH
FRIDKEGKNN IGDVNTNFEY FNYEDISSYH NMKISNSENN NNNYNSVSIF TSKEISKEKK
NKKNDTSIEM RKESPTYIKC NSIEGKTNDK INDIDDENMK VISENLDNNV DINESDNMKR
GCSDNDKNKK EQTFLDSEII NNRYNEHDNI RNYNDKTWSF DNYDTENKID TNEHAYFEGK
SIKINNNCSI YLTLCKNTND CIYSLENYNN VIQEFSFKPP NFSLICQFSL ASIGFKNSKK
LSKKINTCYS LLYEFLSKQK QYTIDLREIK NLLNLVSDDF IRNINVKSEE EIIYDALVEV
NESKLLKDDL NIFYKFLKDL FPLVKKNXEK KKNNETSIKI ITNIMTNMGY TVNDYYINSI
LKLYKIKKTN RGIILVGKSC SGKTSIINIF RHYCDFIKNN NMCNPDNNFP VQSASGAVGN
GIIEENGNDD KKMFTKGNIS YDNVYNIKNK KKIIVNNEDF MNMSQMNNTD ANSKIPNNKN
KYESYNLLSP NNLFCNKYKN QGNSTNIIPN NVVCNKRLST LSVTSSIQSK TTSGPLVDIS
NTYKKGTENN DFNIDVTVFN PMSTDIKKLY GYYNNEKEIY EDGILSLIIK RLFENNNSNE
KWLILDGPLD ILTTEPLHSL LDEHRILTLI NGNRIKFSDN AFIFFEIENL KNCAPSFISR
SKIVFMNAEE FNYEWIVSSY LERNFFNLEE KNLVQGFFNK YVKKIMNAKK NNKYKLIIDV
SDAHIIISIC QLYDMLCNLY DKNFPRNLNP SLCLEKLFLQ SIIYIFSNIL CPKSKELLDH
LIKSIDNTFP HLHTIFDYII SKNNFNWVLW DELITTNHNF LPNVKEHFFS YDNYNFIKND
SNMKYMGVNQ LNETLNPETD FNKFLLSSNL EFSKNFNKYT INYNNLFSDS NNKNTLDEYQ
TYNFNFMSDN GPSNANDINN IDNYNMFSTY SKDHIYSDNN FMDSNVFNAY SKNLSNTYFS
DNTFSNNNFS DNLMSYKNLN NENNNYPNMN NYGNPNINIV NNQISHNENI NNDNMELQNN
NDYNLDNGNL IESYKKSSLK NFYSQKDNLT EINDMHKNKQ KYFQEKFNDN IYIENVESLR
KKNIINILMY NKKNILLIGN KLSGKTFFMK YNILPYIKDD ISTYYTFVSK LYNSNLLEKK
IEINVEKKCR NIYKPIGNKK CLYFILDDLN NLQKYDDNVL NYSDHKNNDD SLLFDFNIDA
SRVAKSGNNS SGKTKSVPNT SILEFLNQFI DYNMYYNRDN ATMKNIENLF FFLIYGNNKK
YTSAFNKKLI NRLHIVHLNE MDEVNIKNTF HVFLRHKFAN FHEVIKNLAE PLSTATIRLF
FECAKKFKPN LNCYHYFFHL KQIFKIIKGI FLSEASIYEE KESFLRLWAN ECFRVLGDQL
ILKNERKVFN NILKKILHKK FYVSYNYLFP KKKTFYFCSY NFHDPKNENP YFFYQPISNE
NLLLEFFKNT ISSYNTFATC NYERKKKEYF RNFNEVMTDP NIKKKTDKDY ISMINAQKEH
VSKESNVRKN LRKGPFNNLI EKNDVTTDDI EQNGVKSGIK NDGNDISNEY VEDGNITKDK
AGIDFQAYNN GLYNANYSTP NLNDEMNISL EKSNKMPKEI EILVNKNDND FNNIKTPINF
ILFKEAMSNV CNFSRIFLFE NEHFISIGDS SPGKFTCALI ACFIYQIKIH VIKNFYYEHT
NALKTPEEDT DTLDRSPLSI LSSDNNSKKN NEELYITKQS NLVDVTKYRH TIGDIEKETD
VLNNMEEKIN DKGYHSLENS NLILHNLKNE DNIKKVSMNL NDMEQTENSE CNMKKTTEIK
INADIEDSNK VISNSTNYNK SGSLIEKLKC NYFIKKFREA LFNCYKNEKR CVLYYLDDNM
NDEILEFLHE LYNNENLINI FNSEEVAYLK NIFLENEISL KKCDTLSEII QELIKKNYHY
VLFTSLKSNI FRKISNEYNV ILKKSTVNYF LSWKNSSYNV IAQEKVKINN INVDVFTILH
NTALKFFEKI FVYIEDEINK KKQNEDNLFS NELIDSMNSS YYTYKNENQY GGTNINKYNE
YDKKHGTDSN IMSKSKNIIL ADNKESMKIN DSIQINTKEN SNVASKKNTK VVQSSKNMND
ISDDCLSTMD DKNDDDMQHN SNYIKSSKLV ENKLNAQKYI NFKHFLNFLQ FFKYLYKKKS
EEINDNEKKI NLALKKLADA KNEIQEMQIK LSLQKENISK KQTECAQLLK EIEEKKKESN
EKKKKIQEDS IRISSVEIET QKLAEDARKD LQNAIPELEV ATQSLEQLDK KSISEVKAYT
KPPDVVMQTL SIVMIILNKN PSWEQAKIEL GDANFLNKLK SFDKDSVSDK TLKKIEKFTK
NPIYSPKAVK KVSAATGALC MWVHALKMYA EVYREVAPKR LRLKLAEELL SKNRKELELA
MEQLAEIEKN LLLLQEQHNE STQKNDELSK SYEESCLRIE NVEKFFLNIT DEKNRWEKYV
KDNERIKKCV YGESILSSFF LVYTGLLNYE DRKFLIYDTC VNLLMKNHIY VNTNFNLVDY
FIDPIQSLEF NINYLSNDVY MKENFILINN NFISNLIIDP HHQVKDWISR SYNNNKTLII
SDFNFPDIFL KIIYCMNNGI PLLINNIKEK LEDILLLTIK KYNKFIMDRE NNNENLIDVK
EKNSSQNDAL IKEYIKKKND LYKNYVNNGY INTSNHNKIS YEEKIYFMKL QLLSGLNIHK
DFKLFLVSNK NCFELDPLFY SLTTVILFNL NSETIDSILL NVIIMNNEKN LEDENKESLL
HLVHVKKEII RLENNILENV TKXQNKITXX XELINILLQS KLQIDQKNGH LEEINDTLNR
MNMNKNTFKP LAKKVSILFT ILNDLKYLNK CYQFSLNHFI NFFIYNINYL KKNLKTVSGS
TNERHEILFN NFFYEFIKHT KISIMIYEDK ISQEDYNFFI FGIKSNAEKE HLNYFKKIHL
IQENRDSIKE NIYNISFKNK GNLHDKKKEK GEKRKRRKPT NIYENKNVNK TTKDDEKNGT
KGTFSDSYNY LDDDEEDDYE DEDDEFGDDD YGYDDENYEE NEEDEEDDEK YCENDELYFE
NSEEYENKGN GNNKDTETNE GLYANTKKNI SNNNADTTEV SDKTKPNHDP MNNKTKRNIK
KKKYNSNKNS NEYSERNYID KPKFNNTSNS RDNQDNTTNS NESISSSNEY KSLEIINPGT
DWISEMQWKY LLDIEKLKNF EGFINSFIKS IREWRRWFNF LEVENNVLPD EWEFNLNSFQ
KLIIIKILRP DRLNKAIENF VCSNISYNDM EVDHMNFEYI LRPYKNVDPI TIIHKSNCDP
FQYVHNYAHK NNQKLKNLIL TSHNINFVDH YLKDAMEKGH ILFISNLPNS ENNLHKLSKI
IDNIFTKSSI TVSSLSKSSS GNSQFRINEK YVSSSDHTGT NYNNNNDNVE KKEYKSGMDE
STITNGIESI KFAESDCNES TNIDRHEIKK NAELNKEIIK NQEKNYFIYE ENICDTLENI
ENYYPLLDDD DNEYSNNMQN LLTKKNNNES IKINDKFRLF LSFLPDDKFP NSLLQKSIIV
ILDEPYNIKK SISILFKEQW VHEEYKNIQL NKYKKVMLSL FWFHSILNNR KKFYNLGWNS
ENYFFSNKDV ILSKHILEMF LNKNIKDIYW PYFHYYICDI IYGSQINDSF DKELLNIYAQ
EFFNDNIFKG KYVFSSCASY YLPPDINNEK ALSNYLKEIP HNDSVEVFGQ KPYSEITYNS
IASEEIISLL FRVNSFHNNQ YNFYNIASNS INEKKIYSFI KTLLHNMPHE IYVDNLIKKD
STQEQYIYVN LMLQEVYKHN MILKKARKSL NKVQYGESTI NFIVPFATIK GETIINKKIY
EIIKSLSDGL VPKSWKIFYI AKKKLINFFE DLNERIKQLN EWSINGYLQI HWLGGFYNPK
SFLKYILHEY SRKNEINHDL LTFEFISISN SDEFKSNSRN SEDGIYIKKV ILQGAKWDFI
NQTLIENDDT NIYSIIPIVY LKVILKKNNK DDNNIYKCPL YIFQEKNILN IKENYLIKVH
LYTYMCS
//
