ID Q7RQE1_PLAYO Unreviewed; 1490 AA.
AC Q7RQE1;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Protein factor associated with neutral-sphingomyelinase activation {ECO:0000313|EMBL:EAA20447.1};
GN ORFNames=PY01158 {ECO:0000313|EMBL:EAA20447.1};
OS Plasmodium yoelii yoelii.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=73239 {ECO:0000313|EMBL:EAA20447.1, ECO:0000313|Proteomes:UP000008553};
RN [1] {ECO:0000313|EMBL:EAA20447.1, ECO:0000313|Proteomes:UP000008553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17XNL {ECO:0000313|EMBL:EAA20447.1,
RC ECO:0000313|Proteomes:UP000008553};
RX PubMed=12368865; DOI=10.1038/nature01099;
RA Carlton J.M., Angiuoli S.V., Suh B.B., Kooij T.W., Pertea M., Silva J.C.,
RA Ermolaeva M.D., Allen J.E., Selengut J.D., Koo H.L., Peterson J.D., Pop M.,
RA Kosack D.S., Shumway M.F., Bidwell S.L., Shallom S.J., van Aken S.E.,
RA Riedmuller S.B., Feldblyum T.V., Cho J.K., Quackenbush J., Sedegah M.,
RA Shoaibi A., Cummings L.M., Florens L., Yates J.R., Raine J.D., Sinden R.E.,
RA Harris M.A., Cunningham D.A., Preiser P.R., Bergman L.W., Vaidya A.B.,
RA van Lin L.H., Janse C.J., Waters A.P., Smith H.O., White O.R.,
RA Salzberg S.L., Venter J.C., Fraser C.M., Hoffman S.L., Gardner M.J.,
RA Carucci D.J.;
RT "Genome sequence and comparative analysis of the model rodent malaria
RT parasite Plasmodium yoelii yoelii.";
RL Nature 419:512-519(2002).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA20447.1}.
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DR EMBL; AABL01000304; EAA20447.1; -; Genomic_DNA.
DR STRING; 73239.Q7RQE1; -.
DR PaxDb; 73239-Q7RQE1; -.
DR EnsemblProtists; EAA20447; EAA20447; EAA20447.
DR InParanoid; Q7RQE1; -.
DR OMA; TYMHTIL; -.
DR Proteomes; UP000008553; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR SMART; SM01026; Beach; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008553}.
FT DOMAIN 318..417
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 425..704
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REGION 160..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..848
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1490 AA; 175346 MW; 54304803952EBD99 CRC64;
MEKNKSRCFN LLFLEEDEEY IDDMLIIMKK IEGNNTIENK GRLRLCSKSL IFEPYNNNED
VLKFXFKKLE NIKLYEIQNE IIIRASEIVK IKTTIHGKKT RCTSQFIYDR KNRKPIGIIN
NYYNDYTNEI KNIDNYNIDE YISIFEKILN NFDQAENNSV TALPNSQDAK GVTGKAGINN
NEKNEDNKVG HNDDNKVGHN DDNNLANAFV CSFRCDGTNL MNKKIKLIYS IAVKIKXGII
IHEKQMEILV SEKKNRHKYL NETGNENDVN NSEFFDGLNG NEEVKRKEIN LELYIQNIID
KLFENTKFDI SSINIHENII SNKIEGFWVF KISPLVKMKG LLNITNKYIY FQAHPNFTNK
KEKKWEIEKI VHVFKRIITM KPNSLEIIFN HPNKKYKSLY IEFVDYNERE IMLNVLKKIK
PESLFINDNP EFLNLVMNKW SNGLITNYEY IDFLNCLSGR SRKDFSQYPV FPWIISDYYS
KEINLNNEKI YRNLSKPVGC LNQNRLDSLI DKMHDHEYFF GSHYSTLAYV VYFLIRIYPE
CQLKLQSGKF DTISRMFVSI ETTFNTALHA NSSFIELIPE FYENNDNFLK NNLNIQANET
ILEDVILPNW CKNANEFLII MKNAMESNYV NQNIHEWINL IFGYKQKGQV AKDNINLFHP
LTYMHTILYE KLSIDRDMRY QNGSHKTPSG YEKFKYNIAA LPKQLLTSQS QTESYNNVEK
NFKDKIKSLI ISMSSKALRT QLHEFGQCPY QLFKENHVQK KSNISFELNK NINNFPWYYS
PVIIELLEDA YYQKSKNISK LGSVNRSRRK CTEIYNSNRE SCESCENDEN DENDENDEND
ENDENDENDE HCEKNNYHFK THMWKLEKVD HIPCDIKGVC SNNNNNICFI CDNGFVKIID
CYDLLNFKNK NNKNFISLKL CDENFSSLTN INSNFILGTI NGNIIFVDTQ NVVKRVNNNN
NRYGAMQNKA RVLNKSKNCD LKKLSKNEEY DSYDTNSICS SFDSVFDYKY CTDTDEDNQK
NIIKIEKNGN FYNKLIKKKI HNDTIRCMSY NNSYLATGSN DETIQLINVE TNFEIVQTYD
NFNSSIKDIE LKNKLLYTRS DKIQLFDIRM PPKNVLNNSN QILNHFTNTI NTSRQNYINN
IINEINIGNY FSNSSQFSNF SQFSNFSQFS NLSQFSNLSQ FSNLSQFSNL SQFSNNCATP
PINTFEKENQ KYNVHIKKKM KNLIFNNCNI NEKNEVDNIN RTYTHFQYLF EKKIKKNINS
IFLNRPCNIV YSSLINDNNI LFIDENKSLY FYDIRAEKWI NRFSNTINNN SKQIYNDKIV
TASSYKNYLC TVDSMGKFLF EPIRFSINFL DNDVTSKLNN TCSILNPTYI NFFNLGFNSF
PDLENTNMLD DISICSHIMF TNLKGDIEIH KKFCIFFFFF RRFLMYINMI ESNTKTALQT
CHKRRCKNGK QNNEVEMARK NGNQNNEVEM ESGACRPFAY LRYKDLLFNN
//
