ID Q7RVQ9_NEUCR Unreviewed; 254 AA.
AC Q7RVQ9;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 2.
DT 24-JAN-2024, entry version 108.
DE SubName: Full=60S ribosomal protein L2 {ECO:0000313|EMBL:EAA28063.2};
GN ORFNames=NCU00413 {ECO:0000313|EMBL:EAA28063.2};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA28063.2, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA28063.2, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
RN [2] {ECO:0007829|PDB:7R81}
RP STRUCTURE BY ELECTRON MICROSCOPY (2.70 ANGSTROMS).
RX PubMed=34815343; DOI=10.1073/pnas.2111862118;
RA Shen L., Su Z., Yang K., Wu C., Becker T., Bell-Pedersen D., Zhang J.,
RA Sachs M.S.;
RT "Structure of the translating Neurospora ribosome arrested by
RT cycloheximide.";
RL Proc. Natl. Acad. Sci. U.S.A. 118:e2111862118-e2111862118(2021).
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL2 family.
CC {ECO:0000256|ARBA:ARBA00005636}.
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DR EMBL; CM002238; EAA28063.2; -; Genomic_DNA.
DR RefSeq; XP_957299.2; XM_952206.3.
DR PDB; 7R81; EM; 2.70 A; D1=1-254.
DR AlphaFoldDB; Q7RVQ9; -.
DR EMDB; EMD-24307; -.
DR STRING; 367110.Q7RVQ9; -.
DR PaxDb; 5141-EFNCRP00000000383; -.
DR EnsemblFungi; EAA28063; EAA28063; NCU00413.
DR GeneID; 3873446; -.
DR KEGG; ncr:NCU00413; -.
DR VEuPathDB; FungiDB:NCU00413; -.
DR HOGENOM; CLU_036235_0_3_1; -.
DR InParanoid; Q7RVQ9; -.
DR OrthoDB; 1086454at2759; -.
DR Proteomes; UP000001805; Chromosome 3, Linkage Group III.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR Gene3D; 2.30.30.30; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 4.10.950.10; Ribosomal protein L2, domain 3; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR014722; Rib_uL2_dom2.
DR InterPro; IPR002171; Ribosomal_uL2.
DR InterPro; IPR022669; Ribosomal_uL2_C.
DR InterPro; IPR022671; Ribosomal_uL2_CS.
DR InterPro; IPR014726; Ribosomal_uL2_dom3.
DR InterPro; IPR022666; Ribosomal_uL2_RNA-bd_dom.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR13691:SF16; 60S RIBOSOMAL PROTEIN L8; 1.
DR PANTHER; PTHR13691; RIBOSOMAL PROTEIN L2; 1.
DR Pfam; PF00181; Ribosomal_L2; 1.
DR Pfam; PF03947; Ribosomal_L2_C; 1.
DR PIRSF; PIRSF002158; Ribosomal_L2; 1.
DR SMART; SM01383; Ribosomal_L2; 1.
DR SMART; SM01382; Ribosomal_L2_C; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
DR PROSITE; PS00467; RIBOSOMAL_L2; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:7R81};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000313|EMBL:EAA28063.2}.
FT DOMAIN 96..231
FT /note="Large ribosomal subunit protein uL2 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01382"
SQ SEQUENCE 254 AA; 27356 MW; 7428117F9E50B41E CRC64;
MGRVIRNQRK GRGSIFTANT RLNKAPAKFR SLDYAERHGY IRGVVKEIIH DPGRGAPLAR
VVFNSPYKFK KQRETFIANE GMYTGQFIYA GKNAALTVGN VLPLGSVPEG TVVSNVEEKV
GDRGAIGRTS GNYVTVVGHN PEEGKTRIKL PSGAKKVVSS SARGMIGIVA GGGRTDKPLL
KASRAKHKFA VKRNSWPKTR GVAMNPVDHP HGGGNHQHIG KASTISRYAA QGQKAGLIAA
RRTGLLRGTQ KTKE
//
