ID Q7RWC1_NEUCR Unreviewed; 446 AA.
AC Q7RWC1;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Alanine-glyoxylate aminotransferase {ECO:0000313|EMBL:EAA26682.1};
GN ORFNames=NCU01821 {ECO:0000313|EMBL:EAA26682.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA26682.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA26682.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CM002237; EAA26682.1; -; Genomic_DNA.
DR RefSeq; XP_955918.1; XM_950825.3.
DR AlphaFoldDB; Q7RWC1; -.
DR STRING; 367110.Q7RWC1; -.
DR PaxDb; 5141-EFNCRP00000001733; -.
DR EnsemblFungi; EAA26682; EAA26682; NCU01821.
DR GeneID; 3872065; -.
DR KEGG; ncr:NCU01821; -.
DR VEuPathDB; FungiDB:NCU01821; -.
DR HOGENOM; CLU_027686_5_1_1; -.
DR InParanoid; Q7RWC1; -.
DR OrthoDB; 3183437at2759; -.
DR Proteomes; UP000001805; Chromosome 6, Linkage Group II.
DR GO; GO:0005777; C:peroxisome; IBA:GO_Central.
DR GO; GO:0008453; F:alanine-glyoxylate transaminase activity; IBA:GO_Central.
DR GO; GO:0004760; F:serine-pyruvate transaminase activity; IBA:GO_Central.
DR GO; GO:0019265; P:glycine biosynthetic process, by transamination of glyoxylate; IBA:GO_Central.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR21152:SF24; ALANINE--GLYOXYLATE AMINOTRANSFERASE 1; 1.
DR PANTHER; PTHR21152; AMINOTRANSFERASE CLASS V; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Aminotransferase {ECO:0000313|EMBL:EAA26682.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Transferase {ECO:0000313|EMBL:EAA26682.1}.
FT DOMAIN 89..406
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 446 AA; 47761 MW; 83E12A9A7139AA6F CRC64;
MPRSSGPVDS PARLSLISRH LAPDYPLNTP YTVERHPDNI DTSLLPKTQT RALTTDTTPA
NMSTQPEHAT LLIPGPIEFD DAVLNSMSHY SESHVGPGFV AVFGETLSML RKLFQTTDPS
AQPFVLSGSG TLGWDLVAAN LIEPGEDALV LSTGYFGDGF ADCLKVYGAN VTQISAEPGS
RPQLPEIEKA LSEKKYKLLT VTHVDTSTGV LSELKNLSEL VHRVSPDTLV IVDGVCSVAC
EEIDFDAWKL DGVVTASQKA IGCPAGLSIS MFSGRAIQAF QNRQTPPTSY FASMKNWLPI
MQNYEAKKPS YFATPSPQLV RALHTALGQI VAQGVKERFA AHKAASDKIK AAVAALGLKQ
VAANPDDQAH GMTAIYLPEN VKGAELLPKL ASRGVVFAGG IHKAIAAKYI RFGHMGVSVL
DPSRGHVEKA IKALEEGLSE CGYQKA
//
