ID Q7S535_NEUCR Unreviewed; 654 AA.
AC Q7S535;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 3.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=Amy1 {ECO:0000313|EMBL:EAA30628.3};
GN Name=gh13-6 {ECO:0000313|EMBL:EAA30628.3};
GN ORFNames=NCU05873 {ECO:0000313|EMBL:EAA30628.3};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA30628.3, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA30628.3, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061}.
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DR EMBL; CM002242; EAA30628.3; -; Genomic_DNA.
DR RefSeq; XP_959864.3; XM_954771.3.
DR AlphaFoldDB; Q7S535; -.
DR STRING; 367110.Q7S535; -.
DR EnsemblFungi; EAA30628; EAA30628; NCU05873.
DR GeneID; 3875996; -.
DR KEGG; ncr:NCU05873; -.
DR VEuPathDB; FungiDB:NCU05873; -.
DR HOGENOM; CLU_024572_2_0_1; -.
DR InParanoid; Q7S535; -.
DR OrthoDB; 2728918at2759; -.
DR Proteomes; UP000001805; Chromosome 7, Linkage Group VII.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11318; AmyAc_bac_fung_AmyA; 1.
DR Gene3D; 2.40.30.140; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR015237; Alpha-amylase_C_pro.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43447; ALPHA-AMYLASE; 1.
DR PANTHER; PTHR43447:SF49; ALPHA-AMYLASE; 1.
DR Pfam; PF09154; Alpha-amy_C_pro; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT DOMAIN 58..498
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT REGION 11..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 654 AA; 73907 MW; 1F012FBCDC9BEB86 CRC64;
MSAFLGLVPQ YPSPTLEPPP PYGGTSSQLR PLRHRRPATS LPSTYTPYPP DAPCPPNRTM
VQGFEWYCPP DFQHWRRLTK IIPTLAQLGI TQIWIPPACK ASWKTGNGYD IYDLYDLGEF
EQKGSRKTKW GGKEELQQLV AVGAQYGVSV LFDAVLNHKA AADFKEPVLA RRVNPKDRRV
VLDRKPTEIE AWTGYDFPGR QGMYSPLRWS ARHFTGIDYD DLRKENAIWK FEGKEWAEDV
DEENGNYDYL MFADIDHQHP EVKRDLFHWT WWLKSQLPQL GGLRLDAIKH YSYSFVREFL
ANIDRHVAPG PPGSPGTWFI VGEYWREDSE FLARYIEFMH HRLSLFDVQL VSNFSRISLA
SEHLQASPTG GGGGAPGITY GSRDTDLRTL FDDTLCIWKP HNAVSFVVNH DTQKGQSLET
PIAPFFMPLA YSLILLRANA GVPCVFWSDL YGSFGVTSND TPASEDAASP RDTPLPDPQH
WKPPMCGGQV LPKLMLARRL WAYGTQYDYL DHPHCVGFTR TGHYSQSGGA GVACVMANWW
EHASKRMYVG VEHAGEVWTD VLKFCPGEVM IDESGWGVFP VAARSVAVWV SRDAEGREGV
DAFELDTDVY GFNQRHQEQV YENQRGPAVE EEPEDWMVAA RGAAAEYLAM TGSD
//
