ID Q7SCP2_NEUCR Unreviewed; 1361 AA.
AC Q7SCP2;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Glycosyltransferase family 28 domain-containing protein {ECO:0000313|EMBL:EAA34516.1};
GN ORFNames=NCU07473 {ECO:0000313|EMBL:EAA34516.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA34516.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA34516.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
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DR EMBL; CM002236; EAA34516.1; -; Genomic_DNA.
DR RefSeq; XP_963752.1; XM_958659.2.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR PaxDb; 5141-EFNCRP00000007402; -.
DR EnsemblFungi; EAA34516; EAA34516; NCU07473.
DR GeneID; 3879901; -.
DR KEGG; ncr:NCU07473; -.
DR VEuPathDB; FungiDB:NCU07473; -.
DR HOGENOM; CLU_000537_1_0_1; -.
DR InParanoid; Q7SCP2; -.
DR OMA; SFAHIHV; -.
DR OrthoDB; 76239at2759; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0016906; F:sterol 3-beta-glucosyltransferase activity; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR004276; GlycoTrans_28_N.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF03033; Glyco_transf_28; 1.
DR SMART; SM00726; UIM; 6.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS50330; UIM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 117..179
FT /note="Glycosyltransferase family 28 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03033"
FT DOMAIN 466..563
FT /note="Erythromycin biosynthesis protein CIII-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06722"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1052..1107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1168..1361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..725
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..791
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..1007
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1052..1074
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1199..1251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1279..1314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1361 AA; 145794 MW; 5D721C645BB6D09B CRC64;
MTQPPNHPQP SSPLSPLSPS VSPPPPAYGD SQDLDHISLS RAGFQAGAAL TPDGRINISI
SEKNHRLSQL LAPALRNQLS GHPPPPLPTT TGPLPPPYIP TSLGGHPGQT PPPKLNVVIQ
IVGSRGDVQP FVALGQTLKQ TYGHRVRVAT HPVFQKFVEE SGLEFFSIGG DPAELMAFMV
KHPGLMPGFD AIKTGEVTKR RKGVMEVLMG CWRSCFEAGD GTGPPPREWK KGDRNAEGVP
MGQDGWTVSS SSGTGGKPFV ADAIIANPPS FAHIHCAEKL EIPLHMMFTM PWSPTRAFAH
PLANIEASNA DVNITNYISY ALVEMMTWQG LGDVINRFRE KVLDLEPLSL LWAPGLLTRL
RIPTTYCWSP ALIPKPNDWA QEISVAGFYF LDLATNYTPE PDLAAFLAAG PPPVYIGFGS
IVVDDPDALT RLILRAVAKS GVRALISKGW GGIGLTEDIT QADWAPRPDQ YFMLGNCPHD
WLFNRVSAVV HHGGAGTSAA GIKAGKPTVV VPFFGDQPFW GAMIAKAGAG PKPIPNKELT
AENLAAAIQE ALKPETLARA KELGNKIKEE KGADEGGKSF HQFLDVDALR CSLSPSRVAT
WRVRRTKVRL SAFAAEVLVR EGLLQYSDLK LFRAKEHITD GQPWDPITAV TAALVEDLGT
MAMSVADFPR GIFKAKEMKR ARNLSGGNGQ ALGSETPADG AHGTSSPQAH GALSPESQPG
SSYFPPTAGD SAEGASRSPS DVKGKGKSVP SGTHSRNDSF RDSFKQRSTS GGGGPSTPGG
TANMSGAATP QLNPEAFSYK SARDATSSVG RLVDTGMKMP MNVCLGLARG FRNAPRLYND
DTVRPQEKVT DFASGLRVAT KEFGFGVYDG LSGLVTQPMR GAEKEGAKGL LKGFAKGLGG
AFLKPGAAIW SIPAYTMQGL NAEVRKLFTG GGWMNHIMAA RAQQGREEME HATREEVRDV
VARWQEKRWE DVAKGGVQGK GKGVFSPGTS TGGASGSSGQ GQTRSGVAAV VGASNDAELE
RAIQASIQQT SNGDPQEDAR VEAAIRLSLA QMQQQMASQT QQPPQHSGTV PARYSDFKSP
SADMASPAAQ PPAYSAEYQH HQPPPEKSSL AQAMIDEYFT GISDEEYQAL IEEAVQQSIR
AQMNQQSTMS AEEEKELLKA IEASKSTYTF GDVPPPPPAY QSSGFTPIAT PSIPNNGEAG
RDLEKEEEEM RKALEESERM DRERREQEER EKQEEAIVLE WVKRQSLAEE RFRGGSQRGL
GGGEGSGGGG GGGSGGGGGQ GQVQRQAQPQ TQTQAHVPRH YQPAQVQSDS RGQGQGIADV
DADGHHGPIQ MEDRDYDEEE EFRRALEESM RISGQGDTRG Q
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