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Database: UniProt
Entry: Q7UWY5_RHOBA
LinkDB: Q7UWY5_RHOBA
Original site: Q7UWY5_RHOBA 
ID   Q7UWY5_RHOBA            Unreviewed;       591 AA.
AC   Q7UWY5;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   05-JUL-2017, entry version 107.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000313|EMBL:CAD72227.1};
GN   OrderedLocusNames=RB1706 {ECO:0000313|EMBL:CAD72227.1};
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetes; Planctomycetia; Planctomycetales;
OC   Planctomycetaceae; Rhodopirellula.
OX   NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD72227.1, ECO:0000313|Proteomes:UP000001025};
RN   [1] {ECO:0000313|EMBL:CAD72227.1, ECO:0000313|Proteomes:UP000001025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC   {ECO:0000313|Proteomes:UP000001025};
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T.,
RA   Ludwig W., Gade D., Beck A., Borzym K., Heitmann K., Rabus R.,
RA   Schlesner H., Amann R., Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp.
RT   strain 1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; BX294135; CAD72227.1; -; Genomic_DNA.
DR   RefSeq; NP_864546.1; NC_005027.1.
DR   RefSeq; WP_011118492.1; NC_005027.1.
DR   ProteinModelPortal; Q7UWY5; -.
DR   STRING; 243090.RB1706; -.
DR   EnsemblBacteria; CAD72227; CAD72227; RB1706.
DR   GeneID; 1792727; -.
DR   KEGG; rba:RB1706; -.
DR   PATRIC; fig|243090.15.peg.790; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   InParanoid; Q7UWY5; -.
DR   KO; K02313; -.
DR   OMA; AGKEHTQ; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001025};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001025}.
FT   DOMAIN      277    410       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      489    558       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   591 AA;  63529 MW;  1168B3F14E82343F CRC64;
     MLTKSMREVC ATGMSSTQGS IETQEAIERF AEALHQRIGA DRYRLWFTHG VGFDLEVGES
     PDDGKPTVVV VIRTSGPFAA QRMGNSFATE LRAAAMIACG ERARYRIDVE EAAQPEPKKR
     TRAAKVAAEK KATTKSGARR SSTRQTSTRA TAGRQSGGRQ SSGRRGSANS LASLLAQSTA
     TGSDQSGGSR GGKGRSRGRV EHDPIAASEL PTDERFDDEE IEDEEVAVST PRSSKSKLPP
     LPESQPTGGR TLDSFITGPC NEFAFSAAMM AVATPSVATP LFLHGPTGTG KSHLLAALAN
     EFRTRRRMRR VVLLTAEQFT NDFVVSVGST GLPAFRRRYR DVDALLIDDV HFLAAKTATL
     REALYTVETL ASAGKPLVFS ANLPPSDIRG LTGEVAGRMA SGLVCPLAAL DQETRFKLLQ
     RMVATRCVLG CDNTLLEEVS ELIGGDARAA GGIANLIGML QRMFRREPTI DEIRRYGGDL
     LRSTQVAPTL RSIEKAVCET FGLEGDGLRG KAQTRRVSEP RTLAMYLARQ HTGSAFTEIA
     KHFGRRSHSN AISAISKVET WLSSGKPIGA GDGAMSAQDA IARVESRLRV G
//
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