ID   Q7UXZ9_RHOBA            Unreviewed;       747 AA.
AC   Q7UXZ9;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Mucin-desulfating sulfatase (N-acetylglucosamine-6-sulfatase) {ECO:0000313|EMBL:CAD71852.1};
DE            EC=3.1.6.14 {ECO:0000313|EMBL:CAD71852.1};
GN   OrderedLocusNames=RB973 {ECO:0000313|EMBL:CAD71852.1};
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC   Rhodopirellula.
OX   NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD71852.1, ECO:0000313|Proteomes:UP000001025};
RN   [1] {ECO:0000313|EMBL:CAD71852.1, ECO:0000313|Proteomes:UP000001025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC   {ECO:0000313|Proteomes:UP000001025};
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA   Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA   Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT   1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
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DR   EMBL; BX294134; CAD71852.1; -; Genomic_DNA.
DR   RefSeq; NP_864175.1; NC_005027.1.
DR   AlphaFoldDB; Q7UXZ9; -.
DR   STRING; 243090.RB973; -.
DR   EnsemblBacteria; CAD71852; CAD71852; RB973.
DR   KEGG; rba:RB973; -.
DR   PATRIC; fig|243090.15.peg.457; -.
DR   eggNOG; COG2755; Bacteria.
DR   eggNOG; COG3119; Bacteria.
DR   HOGENOM; CLU_006332_9_1_0; -.
DR   InParanoid; Q7UXZ9; -.
DR   OrthoDB; 237120at2; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; IEA:UniProtKB-EC.
DR   CDD; cd16031; G6S_like; 1.
DR   CDD; cd01820; PAF_acetylesterase_like; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR013830; SGNH_hydro.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   InterPro; IPR032506; SGSH_C.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   PANTHER; PTHR43108; N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43108:SF8; SD21168P; 1.
DR   Pfam; PF13472; Lipase_GDSL_2; 1.
DR   Pfam; PF16347; SGSH_C; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CAD71852.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001025};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..37
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           38..747
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004295684"
FT   DOMAIN          376..528
FT                   /note="N-sulphoglucosamine sulphohydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16347"
FT   DOMAIN          568..733
FT                   /note="SGNH hydrolase-type esterase"
FT                   /evidence="ECO:0000259|Pfam:PF13472"
SQ   SEQUENCE   747 AA;  84780 MW;  BC7E78937C5BC6CA CRC64;
     MNHLPVSRQA SRMTKRLVAL SIALAVLGNL LPQAASADEP AKAKRPNIVF VFSDDHALQA
     IGAYGSKINK TPNLDRIANE GAVFHNSFCA NSICGPSRAC ILTGKHSHIN GFLRNGNRFD
     GSQVTFPKLL QDVGYQTALI GKWHLGTDPV GFNHWEILPG QGNYYNPDFI QMDGSRKRYT
     GYVTDIITEN TLNWLQNERD EDQPFVLMCQ HKAPHRNWSP PPRHFDLYKG VDVPEPETLF
     DDYSGRSKLL HESEMSLENH FYWGHDMKFH GESLFPEQFL PRLGNGEYRR MNEEQKAAWD
     AAYEPENQKF IADMKAGKLS SKDITKWKYQ RYIKDYLGTV QAVDDSVGEL LAYLDESGLA
     ENTIVIYSSD QGFYLGEHGW YDKRWMFEES LRMPFLIRWP GVIEPGTEST APIQNIDYAP
     TFLEAAGAEI PEAIQGRSMV SMMKDGCRAS STWRDAVYYA YYENAAVHMV PVHDGVRTER
     YKLMFFPRSR EWNLFDLETD PTEMKSVHDD PEYAEILAGL KKRYIDLRDL YDVNTATIPA
     TRGDEPGWQK RNMAMSKLAK TAKPKLAFIG DSITQGWEGR GKKVWEENYA EYDTINLGIG
     GDRTEHIIWR LTHGNLGKIQ PEVAVLMIGT NNTGHFMQDP TQIAEGVEEI LSILREKLPN
     TKIVLQAIMP RGKTKMDLMR LNNIAVNDRI AKMADGENIV YVDLGDHFLN EDGTIDPAIM
     PDYLHLSEKG YEIWADALAP TLESLGL
//