ID Q7VTQ2_BORPE Unreviewed; 313 AA.
AC Q7VTQ2;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=LysR family regulatory protein {ECO:0000313|EMBL:CAE43726.1};
GN OrderedLocusNames=BP3463 {ECO:0000313|EMBL:CAE43726.1};
OS Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257313 {ECO:0000313|EMBL:CAE43726.1, ECO:0000313|Proteomes:UP000002676};
RN [1] {ECO:0000313|Proteomes:UP000002676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251
RC {ECO:0000313|Proteomes:UP000002676};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX640421; CAE43726.1; -; Genomic_DNA.
DR RefSeq; NP_881986.1; NC_002929.2.
DR RefSeq; WP_010931491.1; NZ_CP039022.1.
DR AlphaFoldDB; Q7VTQ2; -.
DR STRING; 257313.BP3463; -.
DR PaxDb; 257313-BP3463; -.
DR GeneID; 69600538; -.
DR KEGG; bpe:BP3463; -.
DR PATRIC; fig|257313.5.peg.3751; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_4; -.
DR Proteomes; UP000002676; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF80; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002676};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 313 AA; 34753 MW; 9BD5A5FF3AAB679D CRC64;
MLNTALRYFL EVVDAGSLTL AAQKLHVAPS AVSRMVRKLE GEHQAQLFER HARGMVLTEA
GQLLKAYARR ASLDAERARA EIRELSQIGQ KLIRVSANQA FGRELLPRVI GEFREIEPTV
RFELNILQSS EINRRVREGE DDIGLSYNLA PPQDVHVQYA RRMPLFAVMA PQHPLAGRDM
LSMQDIGDYP VVLMGPGSTN RFFIDLCCMH EKIELNIAMT CNNQGAIQTC CQQWGAISFS
GDLTVMTPTE RGELVSIPMA NSELHQRIMH IQTMADRQLP ASVGRFVQAL ASRINASYAD
PAWLAAGRGS GAL
//
