ID Q7VX59_BORPE Unreviewed; 649 AA.
AC Q7VX59;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Permease component of branched-chain amino acid transport system {ECO:0000313|EMBL:CAE42231.1};
GN OrderedLocusNames=BP1949 {ECO:0000313|EMBL:CAE42231.1};
OS Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257313 {ECO:0000313|EMBL:CAE42231.1, ECO:0000313|Proteomes:UP000002676};
RN [1] {ECO:0000313|Proteomes:UP000002676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251
RC {ECO:0000313|Proteomes:UP000002676};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. LivHM subfamily. {ECO:0000256|ARBA:ARBA00037998}.
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DR EMBL; BX640416; CAE42231.1; -; Genomic_DNA.
DR RefSeq; NP_880633.1; NC_002929.2.
DR RefSeq; WP_010930654.1; NZ_CP039022.1.
DR AlphaFoldDB; Q7VX59; -.
DR STRING; 257313.BP1949; -.
DR PaxDb; 257313-BP1949; -.
DR KEGG; bpe:BP1949; -.
DR PATRIC; fig|257313.5.peg.2095; -.
DR eggNOG; COG0559; Bacteria.
DR eggNOG; COG4177; Bacteria.
DR HOGENOM; CLU_028469_0_0_4; -.
DR Proteomes; UP000002676; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06582; TM_PBP1_LivH_like; 1.
DR CDD; cd06581; TM_PBP1_LivM_like; 1.
DR InterPro; IPR001851; ABC_transp_permease.
DR InterPro; IPR043428; LivM-like.
DR PANTHER; PTHR11795:SF445; AMINO ACID ABC TRANSPORTER PERMEASE PROTEIN; 1.
DR PANTHER; PTHR11795; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVH; 1.
DR Pfam; PF02653; BPD_transp_2; 2.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002676};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 560..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 594..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 627..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 68623 MW; 621DC522BF8A9BC5 CRC64;
MDLTGFLAQL LNGLAEASSL FLVAAGLSLI FGVTRIVNFA HGSLYMLGVY VAYSIVERVG
GTALGFWFGL VAASLAVGVV GAAIEVVLLR RIYRAPELFQ LLATFALVLV INDAALWIWG
AEDLLGRRAP GLTGAIDLLG RRYPVYNLVL IVVGPVVLGL LWLLLTRTRW GTLVRAATQD
REMLGALGVN QAWLFTGVFA LGAMLAGLGG ALQLPREPAS LSLDLRTIGD AFVIVVVGGM
GSIPGAYVAA LIIAEIKALC IGLGTVTLLG LSISFSKLTL VVEFAFMALV LVFRPWGLFG
RPQGASRNSA PIEAPLRPAA PRLRILWGVL LASLAVLPLL AQWLPYAVVL TQDILIAVLF
AVSLHFMMGP GGMHSFGHAA YFGLGAYGAA LLLKAASLPM EAALAFAPLV GALGALVFGW
FCVRLSGVYL AMLTLAFSQI VWSVVFQWDD FTGGSNGMIG VWPAEWLSGT AYYYLALAVV
AAAVLGLRRV LFSPFGYAMR AGRDSSLRAD AIGIDVKRVQ WAAFVVAGAF GGLAGALYAF
SKGSISPDTM AVSKSVDGLV MVLLGGIQTL IGPVVGATAF NVLQDYIMRA TEYWRALFGG
VILLLVLVFP QGIAGFCRQA GQWWSARAGK DRPPRKGGAF IGGPREKQA
//
