ID Q800F7_TETNG Unreviewed; 568 AA.
AC Q800F7;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Helical cytokine receptor CRFB8 {ECO:0000313|EMBL:CAD67782.1};
GN Name=crfb8 {ECO:0000313|EMBL:CAD67782.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAD67782.1};
RN [1] {ECO:0000313|EMBL:CAD67782.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12869211; DOI=10.1186/1471-2164-4-29;
RA Lutfalla G., Roest Crollius H., Stange-Thomann N., Jaillon O., Mogensen K.,
RA Monneron D.;
RT "Comparative genomic analysis reveals independent expansion of a lineage-
RT specific gene family in vertebrates: the class II cytokine receptors and
RT their ligands in mammals and fish.";
RL BMC Genomics 4:29-29(2003).
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DR EMBL; AJ544894; CAD67782.1; -; Genomic_DNA.
DR AlphaFoldDB; Q800F7; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859:SF89; CYTOKINE RECEPTOR FAMILY MEMBER B8 PRECURSOR; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:CAD67782.1};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..568
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004295624"
FT TRANSMEM 238..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..111
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 123..228
FT /note="Interferon/interleukin receptor"
FT /evidence="ECO:0000259|Pfam:PF09294"
FT REGION 447..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 63848 MW; A8A38DC3BF78ABE2 CRC64;
MWEVLLLDLA AFQCLVSASL PSPTSVFIAS VNLRNVLEWT PGNDTPSNAT FTVQYAIYGD
SDKRRSVRWR ALQRCTNTAQ SWCDLSNQTR DLEEAYYARV RAESRKAWSG WSQTRRFDPK
SDTIFGPPQM SVEVENSNAI VTVKGPMRYQ PNFQMPAVSM ATIYPHMMYN LSIRNTYRNK
TSHFILSSGL YKHHLAEYNK EYCFSVKAKF LAMPVQCQSS EWQCITTPTD PMVRHLQWVV
VSIVVPLVCV YIMGVTGSIL YQYLMGIGQK TPQILDQAFS NQHSLLFPLE RTSLNAITSI
SPADTMTDQR FKDPPPQYAV HLPQETVYNC DDRSIYGLVS ATSHNGEGGN PIKHQKNHSS
GVYAPQTMSS LQRPFHTRLQ KHSAATAESS APEQTAPFQS PLNVKVKMLK ELGVIVLGME
DKSQNELEPL FSGYAAQNTN TAFAAHSEQS EFRLADNEKN GDGHEEEEER VRGTIFIDWD
PKSNKLVLPE LTKWVYRENK PENGWEATKG AAEEENVMGG ELLSGGVCVR QASDKEVLAP
TELGRDPEGA GKVRDILTKW NLVIPMED
//
