ID Q81EX3_BACCR Unreviewed; 549 AA.
AC Q81EX3;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Copper resistance protein {ECO:0000313|EMBL:AAP08812.1};
GN OrderedLocusNames=BC_1838 {ECO:0000313|EMBL:AAP08812.1};
OS Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC
OS 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=226900 {ECO:0000313|EMBL:AAP08812.1, ECO:0000313|Proteomes:UP000001417};
RN [1] {ECO:0000313|EMBL:AAP08812.1, ECO:0000313|Proteomes:UP000001417}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB
RC 9373 / NCTC 2599 / NRRL B-3711 {ECO:0000313|Proteomes:UP000001417};
RX PubMed=12721630; DOI=10.1038/nature01582;
RA Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V.,
RA Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M.,
RA Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G.,
RA Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.;
RT "Genome sequence of Bacillus cereus and comparative analysis with Bacillus
RT anthracis.";
RL Nature 423:87-91(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE016877; AAP08812.1; -; Genomic_DNA.
DR RefSeq; NP_831611.1; NC_004722.1.
DR RefSeq; WP_000114306.1; NZ_CP034551.1.
DR AlphaFoldDB; Q81EX3; -.
DR KEGG; bce:BC1838; -.
DR PATRIC; fig|226900.8.peg.1829; -.
DR HOGENOM; CLU_023176_1_1_9; -.
DR OrthoDB; 2353937at2; -.
DR Proteomes; UP000001417; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR GO; GO:0046688; P:response to copper ion; IEA:InterPro.
DR Gene3D; 2.60.40.1220; -; 1.
DR InterPro; IPR032694; CopC/D.
DR InterPro; IPR007348; CopC_dom.
DR InterPro; IPR008457; Cu-R_CopD_dom.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR032693; YtkA-like_dom.
DR PANTHER; PTHR34820; INNER MEMBRANE PROTEIN YEBZ; 1.
DR PANTHER; PTHR34820:SF4; INNER MEMBRANE PROTEIN YEBZ; 1.
DR Pfam; PF04234; CopC; 1.
DR Pfam; PF05425; CopD; 1.
DR Pfam; PF13115; YtkA; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001417};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..549
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004296055"
FT TRANSMEM 156..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..127
FT /note="CopC"
FT /evidence="ECO:0000259|Pfam:PF04234"
FT DOMAIN 335..427
FT /note="Copper resistance protein D"
FT /evidence="ECO:0000259|Pfam:PF05425"
FT DOMAIN 448..529
FT /note="YtkA-like"
FT /evidence="ECO:0000259|Pfam:PF13115"
SQ SEQUENCE 549 AA; 61797 MW; 780AA922BED46F0A CRC64;
MSVKVMKRLG TLLLLVCVLI ILIPQSASAH AYVVKSNPTE NETLKKAPSV VKIEFDEDIQ
VSRFNTLYVR DTSGKRVDLK DAHIDKKNKK LLEAGLKENL KNGLYSIQWK AISADGHPIQ
GVIPFRIGLA EAETDDVQVE EMGYVPQIDM IMERGILYTS FSLFIGVLFF NLIMYKGNAT
SVRSRSKNII WISLFGILIS LLFNLPLQAK INADVSWLEA FNPLLLKETL QLSVFGYVWI
TQMVLISTLI IVTYFAVKHE KFSSFKVWSI PILLFIGLLV MKAFNSHAYG LKFKDIAVVM
DFLHLFAASL WVGGLSSIIL LLRNEDNKWH MYWDMIKRFS PWATGAVIVI LITGLFNSTF
FIPTIHSLFD TKYGLVLLTK ILLFIFMGIL GIIHYVKGRM RAQQGLGATV KVEFIIGIII
FVIVAFMTNV QTPPMPPTGP FTESKQLDNG YEMTLNVSPN RVGQNIFHIT LKDENGQPVT
DMEQIILTTQ SLDMNMGKGS FKVSAVSPGE YEAEGMYINM TGNWNIQVHG LTKSLDSFDT
DYKFIVGGR
//
