ID Q82HH9_STRAW Unreviewed; 435 AA.
AC Q82HH9;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 119.
DE SubName: Full=NADH dehydrogenase (Complex I) {ECO:0000313|EMBL:BAC71241.1};
GN Name=ndh2 {ECO:0000313|EMBL:BAC71241.1};
GN ORFNames=SAVERM_3529 {ECO:0000313|EMBL:BAC71241.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC71241.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC71241.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC71241.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
CC -!- SIMILARITY: Belongs to the NADH dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00005272}.
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DR EMBL; BA000030; BAC71241.1; -; Genomic_DNA.
DR AlphaFoldDB; Q82HH9; -.
DR KEGG; sma:SAVERM_3529; -.
DR eggNOG; COG1252; Bacteria.
DR HOGENOM; CLU_021377_7_1_11; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0003954; F:NADH dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006116; P:NADH oxidation; IEA:InterPro.
DR Gene3D; 3.50.50.100; -; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR045024; NDH-2.
DR PANTHER; PTHR43706; NADH DEHYDROGENASE; 1.
DR PANTHER; PTHR43706:SF45; NADH DEHYDROGENASE-LIKE PROTEIN RV1812C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT DOMAIN 5..286
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT REGION 415..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 47436 MW; BFAAD1A7E0826277 CRC64;
MRYGEATVTV VDPRSYMTYQ PFLPETAAGS ISPRHVVVPL RRVLPKAEVL TGRVTTIDQD
RKVATIAPLV GEAYELPFDY LVIAMGAVSR TFPIPGLAEQ GIGMKGIEEA IGLRNHVLEQ
LDKADSTTDE EVRRKALTFV FVGGGFAGAE TIGEVEDMAR DAAKYYNNVS REDMRFILVD
AADKILPEVG PKLGQYGKEH LESRGVEIYL STSMDSCVDG HVVLKNGLEV DSSTIVWTAG
VKPNPVLSRF GLPLGPRGHV DTQTTLQVQG TDYIWAAGDN AQVPDMAARK AGVENAWCPP
NAQHALRQAR VLGDNVVSGM RGFPQKEYAH SNKGAVAGLG LHKGVAMIVM GKMKIKLKGR
LAWYMHRGYH GLAMPTWNRK IRVFADWTLQ MFLKREVVAL GALESPREEF YEAAKPAPAP
AAAVAPKTEE KAKAS
//
