ID   Q82Z19_ENTFA            Unreviewed;       328 AA.
AC   Q82Z19;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 111.
DE   SubName: Full=Heptaprenyl diphosphate synthase, component II, putative {ECO:0000313|EMBL:AAO82927.1};
GN   OrderedLocusNames=EF_3260 {ECO:0000313|EMBL:AAO82927.1};
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO82927.1, ECO:0000313|Proteomes:UP000001415};
RN   [1] {ECO:0000313|EMBL:AAO82927.1, ECO:0000313|Proteomes:UP000001415}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA   Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA   Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA   Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA   Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR   EMBL; AE016830; AAO82927.1; -; Genomic_DNA.
DR   RefSeq; NP_816857.1; NC_004668.1.
DR   RefSeq; WP_002372605.1; NZ_KE136524.1.
DR   AlphaFoldDB; Q82Z19; -.
DR   SMR; Q82Z19; -.
DR   STRING; 226185.EF_3260; -.
DR   EnsemblBacteria; AAO82927; AAO82927; EF_3260.
DR   KEGG; efa:EF3260; -.
DR   PATRIC; fig|226185.45.peg.322; -.
DR   eggNOG; COG0142; Bacteria.
DR   HOGENOM; CLU_014015_2_0_9; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR12001:SF87; OCTAPRENYL DIPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001415};
KW   Transferase {ECO:0000256|RuleBase:RU004466}.
SQ   SEQUENCE   328 AA;  36990 MW;  9C915EA115127B7C CRC64;
     MNIHPMWNTY PTLSKELTTT LRLMEQAVQI DNQEIQAAVH DMIHSGGKLL RPAYQLLFSY
     FGEQRDPKKA TALAASIELL HTATLVHDDI VDEADTRRGL PTLRSRFGNS TAVYTGDYLF
     VCCFKLLSDY SSSLKSIQLN SRSMEKVLTG ELGQMDNRYN FEVTIDQYLK NISGKTAELF
     ALSCFVGAYE SGTSQRFAKR CGEIGENIGL AFQIIDDILD YTQTADAIGK PVLEDVRQGV
     YSLPLIYALE ANREVLLPLL MKKEALTDEE TQEIYRLVHE LGGVEKAQEL ATHYTEKALK
     EISKLPETKA QAKEQLYEIT QTILTREN
//