ID Q833S8_ENTFA Unreviewed; 430 AA.
AC Q833S8;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE RecName: Full=Mutator family transposase {ECO:0000256|RuleBase:RU365089};
GN OrderedLocusNames=EF_1855 {ECO:0000313|EMBL:AAO81615.1};
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO81615.1, ECO:0000313|Proteomes:UP000001415};
RN [1] {ECO:0000313|EMBL:AAO81615.1, ECO:0000313|Proteomes:UP000001415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- FUNCTION: Required for the transposition of the insertion element.
CC {ECO:0000256|ARBA:ARBA00002190, ECO:0000256|RuleBase:RU365089}.
CC -!- SIMILARITY: Belongs to the transposase mutator family.
CC {ECO:0000256|ARBA:ARBA00010961, ECO:0000256|RuleBase:RU365089}.
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DR EMBL; AE016830; AAO81615.1; -; Genomic_DNA.
DR RefSeq; NP_815545.1; NC_004668.1.
DR RefSeq; WP_002298157.1; NZ_KE136528.1.
DR AlphaFoldDB; Q833S8; -.
DR STRING; 226185.EF_1855; -.
DR EnsemblBacteria; AAO81615; AAO81615; EF_1855.
DR KEGG; efa:EF1855; -.
DR PATRIC; fig|226185.45.peg.1666; -.
DR eggNOG; COG3328; Bacteria.
DR HOGENOM; CLU_036805_2_0_9; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004803; F:transposase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006313; P:DNA transposition; IEA:UniProtKB-UniRule.
DR InterPro; IPR001207; Transposase_mutator.
DR NCBIfam; NF033543; transpos_IS256; 1.
DR PANTHER; PTHR33217:SF5; MUTATOR FAMILY TRANSPOSASE; 1.
DR PANTHER; PTHR33217; TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS1081; 1.
DR Pfam; PF00872; Transposase_mut; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW ECO:0000256|RuleBase:RU365089};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU365089};
KW Reference proteome {ECO:0000313|Proteomes:UP000001415};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464,
KW ECO:0000256|RuleBase:RU365089};
KW Transposition {ECO:0000256|ARBA:ARBA00022578,
KW ECO:0000256|RuleBase:RU365089}.
FT REGION 53..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..72
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 49521 MW; 00A46DF9EE0F5D93 CRC64;
MARKKRNPDA EKLAESILNA YQPESVDDMQ DALKDVFGPL FEKMLQGELN NHLGYDAHSK
EPKEHDNRRN GYGTKTLKTS FGEVAIDVPR DREASFEPEL IPKRKRDVSD IEGKVLSMYA
RGMSQRDIAA TVEAIYGFDI SHEMISDITD AVLPELEEWQ ARPLAKCYAF LFVDCMYVTL
RENYEAKEYA VYTILGYDLK GNKEILGLWL NQTESKNRWM QVFDELKARG VEDVFFISMD
GVSGLEEGAK AIFPSVIVQR CIVHLVRNAL RYIPSKDYKE VCRDMKKFYG ASSLNAAHAA
FGSFQNRWSH YSGAVDVWKR NFAHVEQLFD YGSAIRKIMY TTNAVESVHS SFRKVTKKGA
FSNENALLKL LYLRTKELHA KWSGGRIQNW AMVLKQLMIN ETFSSRMKSM RFTFRNNGRF
IQLCVRSKFI
//
