ID   Q834J4_ENTFA            Unreviewed;       296 AA.
AC   Q834J4;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 127.
DE   SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:AAO81434.1};
GN   OrderedLocusNames=EF_1656 {ECO:0000313|EMBL:AAO81434.1};
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO81434.1, ECO:0000313|Proteomes:UP000001415};
RN   [1] {ECO:0000313|EMBL:AAO81434.1, ECO:0000313|Proteomes:UP000001415}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA   Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA   Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA   Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA   Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; AE016830; AAO81434.1; -; Genomic_DNA.
DR   RefSeq; NP_815364.1; NC_004668.1.
DR   RefSeq; WP_002369350.1; NZ_KE136528.1.
DR   AlphaFoldDB; Q834J4; -.
DR   STRING; 226185.EF_1656; -.
DR   DNASU; 1200550; -.
DR   EnsemblBacteria; AAO81434; AAO81434; EF_1656.
DR   KEGG; efa:EF1656; -.
DR   PATRIC; fig|226185.45.peg.1855; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_2_9; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd05466; PBP2_LTTR_substrate; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30419:SF8; HTH-TYPE TRANSCRIPTIONAL REGULATOR BSDA; 1.
DR   PANTHER; PTHR30419; HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001415}.
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   296 AA;  34297 MW;  5FB6882C02604AF9 CRC64;
     MNIQLLKYFI EIVNTRSLSA AARNLFVTQP TLSLALKKME SELGTALFDH SDQPFQLTDT
     GVYLYEHGQE VVFQFDQLVT DIREMNQKPV KKQLRLGLTT LFAVQFMKEI SRFLTTHPHV
     NLILQQDGSP KLQTMLANKE IDMGLISFPN TLPEIIHIEP LETTTKGYHV YVVVPESNPL
     SQYEKLTFKD LKDQRFSSLS DNFMIGRLLL DRTRSFGYEP NIILHNDDLQ VLLYSLQKNN
     SICLLPIEYY EVGKSQGLKW IPLKDKFDYF PIGIALRRDF SLTEDVRDFI QIIKEN
//