ID Q84GC7_STRSZ Unreviewed; 264 AA.
AC Q84GC7;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 13-SEP-2023, entry version 49.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
DE Flags: Fragment;
GN Name=hasC {ECO:0000313|EMBL:AAO20099.1};
OS Streptococcus equi subsp. zooepidemicus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=40041 {ECO:0000313|EMBL:AAO20099.1};
RN [1] {ECO:0000313|EMBL:AAO20099.1}
RP NUCLEOTIDE SEQUENCE.
RA Wu X., Gao H.;
RT "Molecular characterization of hyaluronic acid operon from group C
RT Streptococcus equi subsp. zooepidemicus.";
RL Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAO20099.1}
RP NUCLEOTIDE SEQUENCE.
RA Wu X., Gao H., Chen J.;
RT "Molecular cloning, expression, and characterization of hasC and galU, two
RT genes encoding UDP-glucose pyrophosphorylase in group C Streptococcus equi
RT subsp. zooepidemicus.";
RL Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- PATHWAY: Carbohydrate metabolism; nucleotide-sugar metabolism.
CC {ECO:0000256|ARBA:ARBA00005136}.
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY173078; AAO20099.1; -; Genomic_DNA.
DR AlphaFoldDB; Q84GC7; -.
DR UniPathway; UPA00215; -.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259};
KW Transferase {ECO:0000256|RuleBase:RU361259}.
FT DOMAIN 6..261
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT NON_TER 264
FT /evidence="ECO:0000313|EMBL:AAO20099.1"
SQ SEQUENCE 264 AA; 29018 MW; 1D0950CD69D141CE CRC64;
MTKVRKAIIP AAGLGTRFLP ATKALAKEML PIVDKPTIQF IVEEALKAGI EEILVVTGKA
KRSIEDHFDS NFELEYNLQA KGKTELLKLV DETTAINLHF IRQSHPRGLG DAVLQAKAFV
GNEPFVVMLG DDLMDITNPS AKPLTKQLIE DYDCTHASTI AVMRVPHEEV SNYGVIAPQG
KAVKGLYSVE TFVEKPSPDE APSDLAIIGR YLLTPEIFAI LENQAPGAGN EVQLTDAIDK
LNKTQRVFAR EFKGERYDVG DKFG
//
