ID Q84KC4_HORVU Unreviewed; 998 AA.
AC Q84KC4;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=NBS-LRR disease resistance protein homologue {ECO:0000313|EMBL:CAD45031.1};
DE Flags: Fragment;
GN Name=rga S-9203 {ECO:0000313|EMBL:CAD45031.1};
OS Hordeum vulgare (Barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=4513 {ECO:0000313|EMBL:CAD45031.1};
RN [1] {ECO:0000313|EMBL:CAD45031.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12715163;
RA Madsen L.H., Collins N.C., Rakwalska M., Backes G., Sandal N., Krussell L.,
RA Jensen J., Waterman E.H., Jahoor A., Pryor A.J., Langridge P.,
RA Schulze-Lefert P., Stougaard J.;
RT "Barley disease resistance gene analogs of the NBS-LRR class:
RT identification and mapping.";
RL Mol. Genet. Genomics 269:150-161(2003).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; AJ507095; CAD45031.1; -; mRNA.
DR AlphaFoldDB; Q84KC4; -.
DR EnsemblPlants; HORVU.MOREX.r2.7HG0620550.1; HORVU.MOREX.r2.7HG0620550.1; HORVU.MOREX.r2.7HG0620550.
DR EnsemblPlants; HORVU.MOREX.r2.7HG0620550.1.mrna1; HORVU.MOREX.r2.7HG0620550.1.mrna1; HORVU.MOREX.r2.7HG0620550.1.
DR Gramene; HORVU.MOREX.r2.7HG0620550.1; HORVU.MOREX.r2.7HG0620550.1; HORVU.MOREX.r2.7HG0620550.
DR Gramene; HORVU.MOREX.r2.7HG0620550.1.mrna1; HORVU.MOREX.r2.7HG0620550.1.mrna1; HORVU.MOREX.r2.7HG0620550.1.
DR ExpressionAtlas; Q84KC4; baseline and differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF906; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 31..115
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 192..435
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 972..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAD45031.1"
SQ SEQUENCE 998 AA; 113135 MW; F983D8E7DA06734D CRC64;
KGARVHHREN RTRRLASKMA AEALVSVSTG VMNSVLEKLA TLMGEEYTKH KSMQREVAFL
KDELGSMDAV LKKLESIEEE LDPQTREWKN QVMEMAFHIE DCIDNFMHES GEDSNRGGVG
FVGKIAQYIN ALRTRHQFAN QIQQLKTLVK DVSERRKRYK LDECASSSSY VAVDPRVPAL
YTEAANLVGM EGPKEDLIKL LMAEEAESVQ PLRVVSIVGF GGLGKTTLAN QVYHELGGQY
DCKVFVSISQ RPNMMKLLGR IIKKLKMPQA THTDEVQDLI DSIREYLREK RYFFVIDDIW
DESVWGIIRC AFPENQQGSK VITTTRIEMV AKATCNFQHE FVYKMSPLDD QNSRKLFFSR
VGQVDLQPLE EISIEILKKC GGLPLAIVSI ASLLVSQPTR SVTQWKYVCN SLSSNLRTNP
TLEGMRQVLN LSYNNLPHRL KTCLLYIAMY PEDYIIVKAD LLRQWVAEGF IHKVHGQDTN
KVAESYFNEL ANMNMIQPTN IWYDGQVIEC KVHDMILDLI RLKSEEQKFL SVVENLQGMI
PALQSKVRRI FLQLDCGANE CIVQASLSMP YIRSLALFGK SPFKFSMYEL KSIRVLNVHY
EGGLIADRID LTPISNLFHL RYLSINSETK KKYMSISSQK EKMPILILPT LIGDLKHLET
LESCMDITAM PCDIVHLPCL MYLHVPMGTR LPDGIRRMKA LRTLVNFDVH MNSVGNLTGL
SELTNLEFLD FCCDGAERTT SQHAILMDIF WCSVVKLIRC NLKHLCSSSN IFCPPSVELA
SLVTSNTERN LESLHVAATW TFPRVPIWTG QHRKLSQLGI AVERLMQEDI DLLAKLPNLL
YLWLWIRNSP EIRITVRGGE VTFQVLKFFR ITSFAPCLTF MVGAMPKLQK LNLQAHEHGV
ERHGPSTVEG VEHLLKLKQV DIDIYFEGAD TESQRRAAGA EAILMNAISV YPGHPSIKIR
LQSNMEHYFK ISSGSSEGGE EVARQPNDAV DGSTTTDG
//
