ID Q87TP2_VIBPA Unreviewed; 330 AA.
AC Q87TP2;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Putative transcriptional regulator, LysR family {ECO:0000313|EMBL:BAC58290.1};
GN OrderedLocusNames=VP0027 {ECO:0000313|EMBL:BAC58290.1};
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926 {ECO:0000313|EMBL:BAC58290.1, ECO:0000313|Proteomes:UP000002493};
RN [1] {ECO:0000313|EMBL:BAC58290.1, ECO:0000313|Proteomes:UP000002493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633 {ECO:0000313|Proteomes:UP000002493};
RX PubMed=12620739; DOI=10.1016/S0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
RN [2] {ECO:0007829|PDB:3OXN}
RP X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 99-330.
RA Zhang Z., Burley S.K., Swaminathan S.;
RT "The crystal structure of a putative transcriptional regulator from Vibrio
RT parahaemolyticus.";
RL Submitted (SEP-2010) to the PDB data bank.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; BA000031; BAC58290.1; -; Genomic_DNA.
DR RefSeq; NP_796406.1; NC_004603.1.
DR PDB; 3OXN; X-ray; 2.70 A; A/B/C/D=99-330.
DR PDBsum; 3OXN; -.
DR AlphaFoldDB; Q87TP2; -.
DR SMR; Q87TP2; -.
DR DNASU; 1187483; -.
DR KEGG; vpa:VP0027; -.
DR PATRIC; fig|223926.6.peg.27; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_39_3_6; -.
DR EvolutionaryTrace; Q87TP2; -.
DR Proteomes; UP000002493; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08417; PBP2_Nitroaromatics_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR037402; YidZ_PBP2.
DR PANTHER; PTHR30118; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED; 1.
DR PANTHER; PTHR30118:SF15; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3OXN};
KW Reference proteome {ECO:0000313|Proteomes:UP000002493}.
FT DOMAIN 26..83
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 330 AA; 37444 MW; FEF448E1B1329D7A CRC64;
MPEEYNLIKP SHCKCQIVEL EDIYRRDLNL LVALRVLIEE SSVSKAATRL NLSQSAMSRV
LGRLRDLLGD PLFTRQGQHL IPTQKALEID RSLGEPLESL RQLLSPVEFD PQQCDQTFTI
ATTDYAMQTI LPFALPRIYQ EAPNVSFNFL PLQHDRLSDQ LTYEGADLAI CRPTGPVEPL
RSEILGRVGV LCLLSKQHPL ANQEMSLDDY LSHPHAMIAI SDGVKALIEQ ALIDKPQRKM
VLRAYHLEAA LAIVDTLPII ITVPADLAYL VAERYDLVVK PLPFQFTPFD YSMIWHARCE
HSPAQEWLRS VVREECSRLI AKRIEDMGLN
//
