ID   Q89XS0_BRADU            Unreviewed;       326 AA.
AC   Q89XS0;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 124.
DE   SubName: Full=Transcriptional regulatory protein {ECO:0000313|EMBL:BAC45502.1};
GN   OrderedLocusNames=blr0237 {ECO:0000313|EMBL:BAC45502.1};
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=224911 {ECO:0000313|EMBL:BAC45502.1, ECO:0000313|Proteomes:UP000002526};
RN   [1] {ECO:0000313|Proteomes:UP000002526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC   {ECO:0000313|Proteomes:UP000002526};
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC       {ECO:0000256|ARBA:ARBA00003502}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
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DR   EMBL; BA000040; BAC45502.1; -; Genomic_DNA.
DR   RefSeq; NP_766877.1; NC_004463.1.
DR   RefSeq; WP_011083069.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89XS0; -.
DR   STRING; 224911.AAV28_40430; -.
DR   EnsemblBacteria; BAC45502; BAC45502; BAC45502.
DR   GeneID; 64020098; -.
DR   KEGG; bja:blr0237; -.
DR   PATRIC; fig|224911.44.peg.8757; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_3_5; -.
DR   InParanoid; Q89XS0; -.
DR   OrthoDB; 8479870at2; -.
DR   PhylomeDB; Q89XS0; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0010628; P:positive regulation of gene expression; IBA:GO_Central.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30427; TRANSCRIPTIONAL ACTIVATOR PROTEIN LYSR; 1.
DR   PANTHER; PTHR30427:SF1; TRANSCRIPTIONAL ACTIVATOR PROTEIN LYSR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002526};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        90..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   326 AA;  34384 MW;  0784B4FB93F15390 CRC64;
     MNQDVIDIRL LEAFAAVMSA GSITGAARLL GRSQPVVTRQ IQDLEADVGY LLFTRNGPRI
     SPTPKGVLFH AEVERLLMGL KHIRQRANAI GAGALPVLSL AAIPALAAGF VPAALAALER
     KLLPSQVHVQ ALSAENVVQS VLSQSVDFGL ASLPIQHPGL DMQWVCEVPC VACLAMDHPL
     AKKKVIRLRD LAGVRLLTMA NPYRLRRRVE EALEREGVVP AEVIDTNASL TAIAMAKQSL
     GIAVVEPVLT SSLPVEGVVT RPLDVSIPFL FAAIAPTGRE LTPTVAALND ALRAAVALMP
     GAKLHSGAAA LAEAGDETSE FEKAPS
//