ID Q8A8U7_BACTN Unreviewed; 434 AA.
AC Q8A8U7;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Predicted phosphoadenosine phosphosulfate reductase {ECO:0000313|EMBL:AAO76177.1};
GN OrderedLocusNames=BT_1070 {ECO:0000313|EMBL:AAO76177.1};
OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=226186 {ECO:0000313|EMBL:AAO76177.1, ECO:0000313|Proteomes:UP000001414};
RN [1] {ECO:0000313|EMBL:AAO76177.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=12663928; DOI=10.1126/science.1080029;
RA Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA Hooper L.V., Gordon J.I.;
RT "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL Science 299:2074-2076(2003).
RN [2] {ECO:0000313|EMBL:AAO76177.1, ECO:0000313|Proteomes:UP000001414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC VPI-5482 / E50 {ECO:0000313|Proteomes:UP000001414};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
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DR EMBL; AE015928; AAO76177.1; -; Genomic_DNA.
DR RefSeq; NP_809983.1; NC_004663.1.
DR RefSeq; WP_008763519.1; NZ_UYXG01000007.1.
DR AlphaFoldDB; Q8A8U7; -.
DR STRING; 226186.BT_1070; -.
DR PaxDb; 226186-BT_1070; -.
DR EnsemblBacteria; AAO76177; AAO76177; BT_1070.
DR GeneID; 60927044; -.
DR KEGG; bth:BT_1070; -.
DR PATRIC; fig|226186.12.peg.1086; -.
DR eggNOG; COG3969; Bacteria.
DR HOGENOM; CLU_036373_0_0_10; -.
DR InParanoid; Q8A8U7; -.
DR OrthoDB; 9774475at2; -.
DR Proteomes; UP000001414; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0071453; P:cellular response to oxygen levels; IBA:GO_Central.
DR CDD; cd01713; PAPS_reductase; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR021845; DUF3440.
DR InterPro; IPR002500; PAPS_reduct.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR30083:SF0; 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SULFOTRANSFERASE (PAPS REDUCTASE)_FAD SYNTHETASE-RELATED; 1.
DR PANTHER; PTHR30083; UNCHARACTERIZED; 1.
DR Pfam; PF11922; DUF3440; 1.
DR Pfam; PF01507; PAPS_reduct; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001414}.
FT DOMAIN 30..239
FT /note="Phosphoadenosine phosphosulphate reductase"
FT /evidence="ECO:0000259|Pfam:PF01507"
SQ SEQUENCE 434 AA; 51981 MW; 10CAB4B06B3C9C89 CRC64;
MGKKTITGTK NVYELAQERL KVIFNEFDNI YVSFSGGKDS GVLLNMCIDY IRRNNLKIRL
GVFHMDYEIQ YKMTIDYVDR ILEANKDILD VYRVCVPFRV STCTSMYQSF WRPWEDNKKD
IWVRSMPKKA MKKEDFPFYN TTMWDYEFQM RFAQWLHQKK DAVRTCCLIG IRTQESFNRW
RCIYMSRKFQ MYHKYRWTSK VGNDIYNAYP IFDWKTTDVW TANGKFQWDY NVLYDLYYRA
GVNLERQRVA SPFINEAQES LALYRVLDPN TWGKMIGRVN GVNFTGMYGG THAMGWQMVK
LPEGYTWREF MYFLLSTLPE RARKGYLRKL SVSVHFWRTK GGCLSDSTIQ KLIDAKVPII
VMDNSNYKTY KKPVRMEYQD DIDIPEFREI PTYKRMCICI LKNDHACKYM GFSPTKEEMS
KRSQVMEQYR IIVS
//
