ID Q8E1G3_STRA5 Unreviewed; 521 AA.
AC Q8E1G3;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Cell wall surface anchor family protein {ECO:0000313|EMBL:AAM99298.1};
GN OrderedLocusNames=SAG0392 {ECO:0000313|EMBL:AAM99298.1};
OS Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=208435 {ECO:0000313|EMBL:AAM99298.1, ECO:0000313|Proteomes:UP000000821};
RN [1] {ECO:0000313|EMBL:AAM99298.1, ECO:0000313|Proteomes:UP000000821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-611 / 2603 V/R {ECO:0000313|Proteomes:UP000000821};
RX PubMed=12200547; DOI=10.1073/pnas.182380799;
RA Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.,
RA Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D.,
RA Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA DeBoy R.T., Durkin S., Kolonay J.F., Umayam L.A., Madupu R., Lewis M.R.,
RA Radune D., Fedorova N.B., Scanlan D., Khouri H., Mulligan S., Carty H.A.,
RA Cline R.T., Gill J., Scarselli M., Mora M., Iacobini E.T., Brettoni C.,
RA Galli G., Mariani M., Vegni F., Maione D., Rinaudo D., Rappuoli R.,
RA Telford J.L., Kasper D.L., Grandi G., Fraser C.M.;
RT "Complete genome sequence and comparative genomic analysis of an emerging
RT human pathogen, serotype V Streptococcus agalactiae.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002).
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DR EMBL; AE009948; AAM99298.1; -; Genomic_DNA.
DR RefSeq; NP_687426.1; NC_004116.1.
DR RefSeq; WP_000703863.1; NC_004116.1.
DR AlphaFoldDB; Q8E1G3; -.
DR STRING; 208435.SAG0392; -.
DR KEGG; sag:SAG0392; -.
DR PATRIC; fig|208435.3.peg.387; -.
DR HOGENOM; CLU_008941_1_0_9; -.
DR OrthoDB; 2990784at2; -.
DR Proteomes; UP000000821; Chromosome.
DR InterPro; IPR021021; Fibronectin-binding_SSURE.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF11966; SSURE; 2.
DR Pfam; PF04650; YSIRK_signal; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000000821};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 7..25
FT /note="YSIRK Gram-positive signal peptide"
FT /evidence="ECO:0000259|Pfam:PF04650"
FT DOMAIN 483..517
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|Pfam:PF00746"
FT REGION 42..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 56326 MW; C9B57B845CEA86C0 CRC64;
MKISQYNKWS IRRLKVGAAS VMIASGSIVA LGQSHIVSAD EMSQPKTTIT APTANTSTNV
ESSTDKALSK VTTMETSSEM PKMQNMAKVE KTSDKPMMVA TSVRKMMATP TPVAMTKTTS
VDEVKKSTDT AFKQTVDVPA HYVNAAKGNG PFLAGVNQTI PYEAFGGDGM LTRLILKSSE
GAKWSDNGVD KNSPLLPLKG LTKGKYFYQV SLNGNTTGKE GQALLDQIKA NDKHSYQATI
RVYGAKDGKV DLKNMISPKM VTINIPHITT DMEVKNSLKM AFKEKVDVPA KYVSAAKAKG
PFLAGVNETI PYEAFGGDGM LTRLILKASE GAKWSDNGVD KNSPLLPLKD LTKGKYFYQV
SLNGNTAGKK GQALLDQIKA NGSHTYQATI TIYGTKDGKV DMNTILGQKT VMIHINVAKK
DMNSTSMMMK KDKMTMPMKK EMTSSKINTG MMMSNNKMSA NMQMSSQAKS NDKAGKKMSM
MSKNLPNTGE TKQQNVGVLG MLSLAFATGL TALGLKKSKQ R
//
