ID Q8EU54_OCEIH Unreviewed; 472 AA.
AC Q8EU54;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Lysine decarboxylase {ECO:0000313|EMBL:BAC11991.1};
DE EC=4.1.1.18 {ECO:0000313|EMBL:BAC11991.1};
GN OrderedLocusNames=OB0035 {ECO:0000313|EMBL:BAC11991.1};
OS Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS 3954 / HTE831).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=221109 {ECO:0000313|EMBL:BAC11991.1, ECO:0000313|Proteomes:UP000000822};
RN [1] {ECO:0000313|EMBL:BAC11991.1, ECO:0000313|Proteomes:UP000000822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831
RC {ECO:0000313|Proteomes:UP000000822};
RX PubMed=12235376; DOI=10.1093/nar/gkf526;
RA Takami H., Takaki Y., Uchiyama I.;
RT "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT and its unexpected adaptive capabilities to extreme environments.";
RL Nucleic Acids Res. 30:3927-3935(2002).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
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DR EMBL; BA000028; BAC11991.1; -; Genomic_DNA.
DR RefSeq; WP_011064437.1; NC_004193.1.
DR AlphaFoldDB; Q8EU54; -.
DR STRING; 221109.gene:10732197; -.
DR KEGG; oih:OB0035; -.
DR eggNOG; COG1982; Bacteria.
DR HOGENOM; CLU_025925_2_1_9; -.
DR PhylomeDB; Q8EU54; -.
DR Proteomes; UP000000822; Chromosome.
DR GO; GO:0008923; F:lysine decarboxylase activity; IEA:UniProtKB-EC.
DR CDD; cd00615; Orn_deC_like; 1.
DR Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:BAC11991.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000000822}.
FT DOMAIN 9..300
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 389..452
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
SQ SEQUENCE 472 AA; 52988 MW; A4070595637BCB73 CRC64;
MKLDQSYMPF VDHLRNFSSK RPVSFHVPGH KHGAVFPEAA RELFGSILSV DVTEIAGMDD
LHAPSEIIAE AEKLATDYFN SDHTFFLVGG STSGNLAMIM AACNPGDEVI VQRNCHKSIM
NGLELAGAKP IFIAPEWRDD LQRYTAPTYD SIKQAMLRFP NAKALILTYP DYFGAVFDIQ
SMIELAHTYH IPVFVDEAHG VHFSSSEMFP QSALQLGADV VVQSAHKMAP AMTMAAYLHI
GTSRVEKHRL AYYLQMLQSS SPSYPIMASL DVARFYLAQL SKEKIRGILN SVENVRNIFS
GASFWELVPH DDPLKLTFHV KHGYKISEIE SMLEYHGIYP ELTTENQFLF IHGLAPFVEQ
DYLKKTIQLI EEELKKSVKH ATIEGAKLFT NPIEELALSY QEMKHITSLL VPFAQSEGEI
AAEAVIPYPP GIPVILKGER ITKAHITKIQ LLIQQGVTIQ QREEGIRIYR KA
//
