ID Q8EZK2_LEPIN Unreviewed; 330 AA.
AC Q8EZK2;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 2.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Hydrolase {ECO:0000313|EMBL:AAN51049.2};
GN OrderedLocusNames=LA_3851 {ECO:0000313|EMBL:AAN51049.2};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN51049.2, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN51049.2, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN51049.2,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC family. {ECO:0000256|ARBA:ARBA00010884}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE010300; AAN51049.2; -; Genomic_DNA.
DR RefSeq; NP_714031.2; NC_004342.2.
DR AlphaFoldDB; Q8EZK2; -.
DR ESTHER; lepin-LA3851; abh_upf0017.
DR PaxDb; 189518-LA_3851; -.
DR EnsemblBacteria; AAN51049; AAN51049; LA_3851.
DR KEGG; lil:LA_3851; -.
DR PATRIC; fig|189518.3.peg.3823; -.
DR HOGENOM; CLU_032487_0_1_12; -.
DR InParanoid; Q8EZK2; -.
DR OrthoDB; 332676at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0047372; F:acylglycerol lipase activity; IBA:GO_Central.
DR GO; GO:0034338; F:short-chain carboxylesterase activity; IBA:GO_Central.
DR GO; GO:0044255; P:cellular lipid metabolic process; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR012020; ABHD4.
DR InterPro; IPR022742; Hydrolase_4.
DR PANTHER; PTHR10794; ABHYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10794:SF63; ALPHA_BETA HYDROLASE 1, ISOFORM A; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PIRSF; PIRSF005211; Ab_hydro_YheT; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AAN51049.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408}.
FT DOMAIN 66..283
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
SQ SEQUENCE 330 AA; 38199 MW; 83E6C37BDBD4371E CRC64;
MNLKKLKTPK FTPSGILKSP FIQTALASLK WNLPKEMTFL KNTEKMILDV GKGVRLEGYL
SKQKNQKPKG FLILLHGWEG SVNSTYILKT SNYFYEKKYN IFRLNYRDHG ETHHLNPEPF
NGSLLEETYE AVLKVVTFAD KGIPIFIIGF SLGGNFTLRI ARLHSQSKNK IKQLKECIAI
SPAIHPKDAT ILMDQKLIIG RYFLKKWKQS ILKKQKHFPA LIPYDKILKE KSVMKMTEKM
INSTEEFKDL DHYFGTYTLG EKELSQILIP TTILTAKDDP IIRGESFLSL HPNRNVRISI
QDFGGHNGFL ENWKGACWYF RVLDEIFSEY
//
