ID Q8F4D4_LEPIN Unreviewed; 343 AA.
AC Q8F4D4;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=ATP-grasp enzyme {ECO:0000313|EMBL:AAN49306.1};
GN OrderedLocusNames=LA_2107 {ECO:0000313|EMBL:AAN49306.1};
OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS 56601).
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN49306.1, ECO:0000313|Proteomes:UP000001408};
RN [1] {ECO:0000313|EMBL:AAN49306.1, ECO:0000313|Proteomes:UP000001408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=56601 {ECO:0000313|EMBL:AAN49306.1,
RC ECO:0000313|Proteomes:UP000001408};
RX PubMed=12712204; DOI=10.1038/nature01597;
RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X.,
RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., Gu W.Y.,
RA Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., Wan M.,
RA Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., Qiang B.Q.,
RA Xia Q.C., Guo X.K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.M.,
RA Shi M.H., Chen Z., Xu J.G., Zhao G.P.;
RT "Unique physiological and pathogenic features of Leptospira interrogans
RT revealed by whole-genome sequencing.";
RL Nature 422:888-893(2003).
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DR EMBL; AE010300; AAN49306.1; -; Genomic_DNA.
DR RefSeq; NP_712288.1; NC_004342.2.
DR RefSeq; WP_001191099.1; NC_004342.2.
DR AlphaFoldDB; Q8F4D4; -.
DR STRING; 189518.LA_2107; -.
DR PaxDb; 189518-LA_2107; -.
DR EnsemblBacteria; AAN49306; AAN49306; LA_2107.
DR GeneID; 61141707; -.
DR KEGG; lil:LA_2107; -.
DR PATRIC; fig|189518.3.peg.2101; -.
DR HOGENOM; CLU_053807_0_0_12; -.
DR InParanoid; Q8F4D4; -.
DR OrthoDB; 9803907at2; -.
DR Proteomes; UP000001408; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0018169; F:ribosomal S6-glutamic acid ligase activity; IBA:GO_Central.
DR GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013651; ATP-grasp_RimK-type.
DR InterPro; IPR040657; GshAB_ATP-grasp.
DR InterPro; IPR020561; PRibGlycinamid_synth_ATP-grasp.
DR PANTHER; PTHR21621:SF0; BETA-CITRYLGLUTAMATE SYNTHASE B-RELATED; 1.
DR PANTHER; PTHR21621; RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN; 1.
DR Pfam; PF18419; ATP-grasp_6; 1.
DR Pfam; PF01071; GARS_A; 1.
DR Pfam; PF08443; RimK; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000001408}.
FT DOMAIN 89..342
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 343 AA; 38680 MW; 0771B98B7A7BCDF0 CRC64;
MQSLKLKPGE FLSPEKFVLE GFEDLEISTQ IVLRDALNRG LEVEILDRKN HFLRLKNQNG
LVQYVKEASK TALDSYITFL VMENKTISKI IMYEYNLQVP AGDSFIDSES ALFFWQKNLD
RKMVVKPVTT NFGIGISVLP PRTSEEDAKK AIKIAFNHSE SIIVEEFAEG NEYRFLVIGE
ETVAVCNRIP ANVTGDGIHT IQDLVSFKNE DPRRGVGHVT PLEKIQLGDT ELDVLQQSGF
TKDFIPAKDQ KVFLRKNSNI STGGDSMDVT DLAHPYYKEL AVKAAKSVGA KICGVDIILQ
DLEKKGDYRI LELNFNPVLY IHNYPYEGKN RDVGNKILDL LGF
//
