ID Q8G8D0_BURCE Unreviewed; 334 AA.
AC Q8G8D0;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE RecName: Full=Protein RecA {ECO:0000256|ARBA:ARBA00015553, ECO:0000256|RuleBase:RU000526};
DE AltName: Full=Recombinase A {ECO:0000256|RuleBase:RU000526};
DE Flags: Fragment;
GN Name=recA {ECO:0000313|EMBL:AAN76873.1};
OS Burkholderia cepacia (Pseudomonas cepacia).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=292 {ECO:0000313|EMBL:AAN76873.1};
RN [1] {ECO:0000313|EMBL:AAN76884.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 17460 {ECO:0000313|EMBL:AAN76884.1};
RA Mahenthiralingam E., Fadden J.D.;
RT "Phylogenetic diversity of the Burkholderia cepacia complex based on the
RT recA gene.";
RL Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAN76873.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 17769 {ECO:0000313|EMBL:AAN76873.1}, CEP1061
RC {ECO:0000313|EMBL:AAN76876.1}, and LMG 6860
RC {ECO:0000313|EMBL:AAN76925.1};
RX PubMed=16000805; DOI=10.1128/AEM.71.7.3917-3927.2005;
RA Payne G.W., Vandamme P., Morgan S.H., Lipuma J.J., Coenye T.,
RA Weightman A.J., Jones T.H., Mahenthiralingam E.;
RT "Development of a recA gene-based identification approach for the entire
RT Burkholderia genus.";
RL Appl. Environ. Microbiol. 71:3917-3927(2005).
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000256|ARBA:ARBA00025580}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000256|ARBA:ARBA00009391,
CC ECO:0000256|RuleBase:RU004527}.
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DR EMBL; AF456008; AAN76873.1; -; Genomic_DNA.
DR EMBL; AF456011; AAN76876.1; -; Genomic_DNA.
DR EMBL; AF456019; AAN76884.1; -; Genomic_DNA.
DR EMBL; AF456069; AAN76925.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8G8D0; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd00983; RecA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049261; RecA-like_C.
DR InterPro; IPR049428; RecA-like_N.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C_sf.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02012; tigrfam_recA; 1.
DR PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1.
DR PANTHER; PTHR45900; RECA; 1.
DR Pfam; PF00154; RecA; 1.
DR Pfam; PF21096; RecA_C; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54752; RecA protein, C-terminal domain; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004527};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU004527};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW ECO:0000256|RuleBase:RU004527};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU000526};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004527};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004527};
KW SOS response {ECO:0000256|RuleBase:RU000526}.
FT DOMAIN 29..188
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 193..266
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAN76873.1"
FT NON_TER 334
FT /evidence="ECO:0000313|EMBL:AAN76873.1"
SQ SEQUENCE 334 AA; 35806 MW; DA06F4A8CCF5846A CRC64;
ALAAALAQIE KQFGKGSIMR MGDGEATENI QVVSTGSLGL DIALGVGGLP RGRVVEIYGP
ESSGKTTLTL QVIAELQKIG GTAAFIDAEH ALDVQYAAKL GVNVPELLIS QPDTGEQALE
ITDALVRSGS IDMIVIDSVA ALVPKAEIEG EMGDSLPGLQ ARLMSQALRK LTGTIKRTNC
LVIFINQIRM KIGVMFGNPE TTTGGNALKF YSSVRLDIRR IGSIKKNDEV IGNETRVKVV
KNKVSPPFRE AIFDILYGEG ISRQGEIIDL GVQAKIVDKA GAWYSYNGEK IGQGKDNARE
FLRENPEIAR EIENRIRESL GVVAMPDGAG QDEA
//
