ID   Q8IAI0_9MUSC            Unreviewed;       355 AA.
AC   Q8IAI0;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   24-JAN-2024, entry version 69.
DE   RecName: Full=alpha-amylase {ECO:0000256|ARBA:ARBA00012595};
DE            EC=3.2.1.1 {ECO:0000256|ARBA:ARBA00012595};
DE   Flags: Fragment;
GN   Name=Amy {ECO:0000313|FlyBase:FBgn0021024};
OS   Drosophila triauraria.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=67534 {ECO:0000313|EMBL:BAC53960.1};
RN   [1] {ECO:0000313|EMBL:BAC53960.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Yakushima Is. {ECO:0000313|EMBL:BAC53960.1};
RA   Zhang Z., Inomata N., Cariou M., Yamazaki T.;
RT   "Molecular Phylogeny and Evolution of the Amylase Multigenes in the
RT   Drosophila montium Species Subgroup.";
RL   Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC         polysaccharides containing three or more (1->4)-alpha-linked D-
CC         glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|ARBA:ARBA00000548};
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- COFACTOR:
CC       Name=chloride; Xref=ChEBI:CHEBI:17996;
CC         Evidence={ECO:0000256|ARBA:ARBA00001923};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061, ECO:0000256|RuleBase:RU003615}.
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DR   EMBL; AB048696; BAC53960.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8IAI0; -.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   FlyBase; FBgn0021024; Dtra\Amy.
DR   GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11317; AmyAc_bac_euk_AmyA; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR006046; Alpha_amylase.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR43447; ALPHA-AMYLASE; 1.
DR   PANTHER; PTHR43447:SF49; ALPHA-AMYLASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PRINTS; PR00110; ALPHAAMYLASE.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Chloride {ECO:0000256|ARBA:ARBA00023214};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          1..345
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAC53960.1"
FT   NON_TER         355
FT                   /evidence="ECO:0000313|EMBL:BAC53960.1"
SQ   SEQUENCE   355 AA;  38989 MW;  5C27F8EC3EAD56EB CRC64;
     PNGFAGVQVS PVNENAVKDS RPWWERYQPI SYKLVTRSGN EEQFASMVRR CNKAGVRIYV
     DVIFNHMAAD GGTYGTGGST ASPSSKSYPG VPYSSLDFNS TCAINNYNDA NQVRNCELVG
     LRDLNQGNSY VQDKVVEFLD HLIDLGVAGF RVDAAKHMWP ADLGVIYRRL KNLNTDHGFA
     SGAKAYIVQE VIDMGGEAIS KNEYTGLGAI TEFRHSDSIG KAFRGKDQLR YMSNWGTGWG
     FAASDRSLVF VDNHDNQRGH GAGGADVLTY KVPKQYKMAS AFMLAHPFGT PRVMSSFSFS
     NTDQGPPTTD GHNIASPTFN SDNSCSGGWV CEHRWRQIYN MVAFRNAVGS DGLQN
//