ID Q8IHU8_PLAF7 Unreviewed; 313 AA.
AC Q8IHU8;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=OTU domain-containing protein, putative {ECO:0000313|EMBL:CZT99080.1};
GN ORFNames=PF3D7_1141700 {ECO:0000313|EMBL:CZT99080.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT99080.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|EMBL:CZT99080.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
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DR EMBL; LN999945; CZT99080.1; -; Genomic_DNA.
DR RefSeq; XP_001348098.1; XM_001348062.1.
DR AlphaFoldDB; Q8IHU8; -.
DR SMR; Q8IHU8; -.
DR STRING; 36329.Q8IHU8; -.
DR PaxDb; 5833-PF11_0428; -.
DR EnsemblProtists; CZT99080; CZT99080; PF3D7_1141700.
DR GeneID; 810974; -.
DR KEGG; pfa:PF3D7_1141700; -.
DR VEuPathDB; PlasmoDB:PF3D7_1141700; -.
DR HOGENOM; CLU_895673_0_0_1; -.
DR InParanoid; Q8IHU8; -.
DR OMA; ICFHHKL; -.
DR OrthoDB; 242020at2759; -.
DR PhylomeDB; Q8IHU8; -.
DR Proteomes; UP000001450; Chromosome 11.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IBA:GO_Central.
DR GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR CDD; cd22748; OTU_OTUD6-like; 1.
DR Gene3D; 3.90.70.80; -; 2.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR12419:SF10; DEUBIQUITINASE OTUD6B; 1.
DR PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF02338; OTU; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50802; OTU; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT DOMAIN 134..311
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT REGION 56..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 37664 MW; EEA7503055385DB2 CRC64;
MEEEGRISYH EYKRRLKKLT EEIKKEMKKS SNKNKKSETL LNLEEKLNKL NELYNKEDDN
KKVEENYNND DNNKDDPFHT NTLYQMNVMS KKALRNRKKM EHREYEEEQI EKSRNKEGEK
EYEELSLNLK KLNKTIYSIA PDGNCLYESI IHQLKYRIHT YQYTITDFLK LINKEQFSLD
NINLKDYINT NFFNFNIFNN INPNDLSSDL LRFITSIYLL QNKELFINFI YDSDDCEDND
TYFKYCEDII KGVYGSEIEI KALSNILKKK ITVYDVNMNI SYEEDCEEEL FLCFHHKLYA
LGKHYNSVID LPS
//
