ID Q8IKT8_PLAF7 Unreviewed; 511 AA.
AC Q8IKT8;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 24-JAN-2024, entry version 133.
DE SubName: Full=RNA-binding protein, putative {ECO:0000313|EMBL:CZU00235.1};
GN ORFNames=PF3D7_1454000 {ECO:0000313|EMBL:CZU00235.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CZU00235.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|EMBL:CZU00235.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
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DR EMBL; LN999946; CZU00235.1; -; Genomic_DNA.
DR RefSeq; XP_001348687.1; XM_001348651.1.
DR AlphaFoldDB; Q8IKT8; -.
DR SMR; Q8IKT8; -.
DR STRING; 36329.Q8IKT8; -.
DR PaxDb; 5833-PF14_0513; -.
DR EnsemblProtists; CZU00235; CZU00235; PF3D7_1454000.
DR GeneID; 812095; -.
DR KEGG; pfa:PF3D7_1454000; -.
DR VEuPathDB; PlasmoDB:PF3D7_1454000; -.
DR HOGENOM; CLU_453819_0_0_1; -.
DR InParanoid; Q8IKT8; -.
DR OMA; IFCEYES; -.
DR OrthoDB; 1343740at2759; -.
DR PhylomeDB; Q8IKT8; -.
DR Proteomes; UP000001450; Chromosome 14.
DR GO; GO:0003723; F:RNA binding; ISS:GeneDB.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd12374; RRM_UHM_SPF45_PUF60; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR040052; RBM17.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR PANTHER; PTHR13288:SF8; SPLICING FACTOR 45; 1.
DR PANTHER; PTHR13288; SPLICING FACTOR 45 SPF45; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 348..394
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT DOMAIN 417..501
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..72
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 511 AA; 59423 MW; F7CFC389EAF59CAB CRC64;
MDSLYGDLPP PVSSNKKTGG NNEKKNLINE EKNNYIGFNK FLITPAIVQK NIANTKKEKK
ELEKKNSGNE DEENEGQSDD EEDIFWNHLK DGNVKNKVEK NNLNIKKKEK INETTTNIEI
INMNKSIQDD LKKISDRLNK IQHNYKNEQV PINSNKNIKE LFVNNNFETD IKHTKSNHYQ
IDNLLNHENM ENDTFQYDLY EKYFIANANE DYEPNKPNDL IKIIKERKRK KIIMLAEQKK
KLEMEEMDDS PEKDTNNVNC YERKNSNINS LKNMELDYEK KRKLNEFDDL KGYDEERKKK
ETDIRKSIDN NMSNHPSDDD YTYNYGNINH NENSYNSNDD NKDTTTSKKD FATRMMEKMG
WKKGEGLGKD KQGIKAPLIL KKVDKRSGVI VQAPVILKNN DLNNKGENLS VPNDCTRIVH
LTNLVTPEEV DETLKEEIEE EASKFGNLLN INIVVDKNLL DALAVKIYCE YESKDQAQNA
LNTFKGRTFA GRKVQASFAT EEEYETLENN D
//
