ID Q8ILL1_PLAF7 Unreviewed; 406 AA.
AC Q8ILL1;
DT 01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Enoyl-CoA hydratase, putative {ECO:0000313|EMBL:CZT99947.1};
DE EC=4.2.1.17 {ECO:0000313|EMBL:CZT99947.1};
GN ORFNames=PF3D7_1425200 {ECO:0000313|EMBL:CZT99947.1};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT99947.1, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|EMBL:CZT99947.1, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN999946; CZT99947.1; -; Genomic_DNA.
DR RefSeq; XP_001348406.1; XM_001348370.1.
DR AlphaFoldDB; Q8ILL1; -.
DR SMR; Q8ILL1; -.
DR STRING; 36329.Q8ILL1; -.
DR PaxDb; 5833-PF14_0232; -.
DR EnsemblProtists; CZT99947; CZT99947; PF3D7_1425200.
DR GeneID; 811814; -.
DR KEGG; pfa:PF3D7_1425200; -.
DR VEuPathDB; PlasmoDB:PF3D7_1425200; -.
DR HOGENOM; CLU_644785_0_0_1; -.
DR InParanoid; Q8ILL1; -.
DR OMA; CNTIQHL; -.
DR OrthoDB; 240183at2759; -.
DR PhylomeDB; Q8ILL1; -.
DR Reactome; R-PFA-70895; Branched-chain amino acid catabolism.
DR Proteomes; UP000001450; Chromosome 14.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR PANTHER; PTHR11941:SF54; ENOYL-COA HYDRATASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11941; ENOYL-COA HYDRATASE-RELATED; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CZT99947.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT REGION 26..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 48259 MW; E627CF0FFDE83BF2 CRC64;
MHVNCKKKKT CSYFIKRYIN TPRDSDIASS LPSEKEKKFN EEKSVHKENA SEGENILACE
EERQYFKNHK YVDFFRDESR SIGLITFKNM NEKKNIFYNF LEELKNVLEH VNNIISNEEN
NTFYIKEFKN KENYLIKNIK NCIPYYDNKL KILIIHSVMD NNIFLNSLDY NSYLKNDEDT
NVEISNIFRF LCNTIQQLPI ITISNINGLC LNSGIDLILS TDFKISKENS LFGFDKMHIG
LYPYGGSCQK LFRHIPLNYA KYLLLTNKII NAQDALKINL IDICIKQNEN FFIQNSNIYF
EQNLSNEQIF SIIKENILNY FKDIFHHHLF QKKINDDSFI FTLFYSFQFL FIPTYILQNI
KVGINEGLNF NDVNSYLDYD RHMFEKCINS IPRLDILNYI KKKKNQ
//
