ID   Q8KC77_CHLTE            Unreviewed;       955 AA.
AC   Q8KC77;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   SubName: Full=Peptidase, M16 family {ECO:0000313|EMBL:AAM72774.1};
GN   OrderedLocusNames=CT1548 {ECO:0000313|EMBL:AAM72774.1};
OS   Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
OS   (Chlorobium tepidum).
OC   Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC   Chlorobaculum.
OX   NCBI_TaxID=194439 {ECO:0000313|EMBL:AAM72774.1, ECO:0000313|Proteomes:UP000001007};
RN   [1] {ECO:0000313|EMBL:AAM72774.1, ECO:0000313|Proteomes:UP000001007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49652 / DSM 12025 / NBRC 103806 / TLS
RC   {ECO:0000313|Proteomes:UP000001007};
RX   PubMed=12093901; DOI=10.1073/pnas.132181499;
RA   Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J.,
RA   Deboy R., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D.,
RA   Durkin A.S., Kolonay J.L., Yang F., Holt I., Umayam L.A., Mason T.,
RA   Brenner M., Shea T.P., Parksey D., Nierman W.C., Feldblyum T.V.,
RA   Hansen C.L., Craven M.B., Radune D., Vamathevan J., Khouri H., White O.,
RA   Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A.,
RA   Fraser C.M.;
RT   "The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic,
RT   anaerobic, green-sulfur bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006470; AAM72774.1; -; Genomic_DNA.
DR   RefSeq; NP_662432.1; NC_002932.3.
DR   AlphaFoldDB; Q8KC77; -.
DR   STRING; 194439.CT1548; -.
DR   EnsemblBacteria; AAM72774; AAM72774; CT1548.
DR   KEGG; cte:CT1548; -.
DR   eggNOG; COG0612; Bacteria.
DR   HOGENOM; CLU_306466_0_0_10; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000001007; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001007};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          44..85
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          240..410
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          730..860
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   955 AA;  109749 MW;  96F24DEF43D8903F CRC64;
     MTETKTNQNE SYPYTTVPGD ALQTRIYTLK NGLTVYMSPY HDEPRIYTSI AVRAGSKNDP
     AETTGLAHYL EHMLFKGTDS IGSIDYAKEH TELEKIIELY EQYRATSDPE HRAAIYRDID
     SISNVAAQFT VPNEYDKLLN SIGAKGTNAY TWVEQTVYIN DIPSNELDRW LTIEAERFRN
     PVMRLFHTEL ETVYEEKNMT MDSDSRKLWE ELFKGLFTKH TYGTQTTIGK AEHLKKPSIK
     NVIDYYRSWY VPNNMALCIA GDFDPDATIR LIDEKFSKLE PKPVPEFHPP VEPEITRPVV
     KTVTGPEAEE LVLGFRFGGA DSDDADMLTL IDKILFNQTA GLIDLNLNQQ QKVLEGGSML
     VLMKDYSVHI LSAKPRDGQS LDEVKALLLE QLDLVKKGEF PDWLVTAVIN DLKLEELKAF
     ESNRGRSEAF VDTFVWGMDW ARQVNRFKRL EKITKAEIVE FAKQHYAQNY VAVYKKHGQR
     KSEAKIQKPP ITPIKVNRDR SSVFAKNLLA KKSSKVQPVF VDFKKDIGYY DITPEISLNY
     VPNRENELYS LYFMFDAGSN LNRKIDTALD YLSYLGTSRL SPAEFSQELY RLGAQFTVQT
     SDNYVYLKLS GLKENFPQAI SLLDELLRDA QPDAPALEKL KEGIRKERAD EKLSKRKILF
     EAMVNYGKYG PKSPFTNVLS DEEIDKLTPE ELLGEIKHFM NYRHRVLYYG PDSPETLMTE
     LRTMHHFGQS FQPVPVTDPF EELKTAKNHV YVVDYDMTQA EIIMLSRGAV YDASKVPLVT
     LFNEYYGGGM SSVVFQEMRE AKALAYSVFS VYRLPKEKDR HSYVFSYIGT QADKLPEALD
     GFNELMQKLP ESPELFASAK AGIDQKIRTE RITKGDVLFA LEEARRLGLD HDIRQDVFRE
     VPGMSFSDIE QFHETRFRNK PQIMLVLGKK EQLDLETLRK YGDISFLTLR EIFGY
//