ID   Q8KDY3_CHLTE            Unreviewed;       991 AA.
AC   Q8KDY3;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Type III restriction system endonuclease {ECO:0000313|EMBL:AAM72146.1};
GN   Name=res {ECO:0000313|EMBL:AAM72146.1};
GN   OrderedLocusNames=CT0911 {ECO:0000313|EMBL:AAM72146.1};
OS   Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
OS   (Chlorobium tepidum).
OC   Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC   Chlorobaculum.
OX   NCBI_TaxID=194439 {ECO:0000313|EMBL:AAM72146.1, ECO:0000313|Proteomes:UP000001007};
RN   [1] {ECO:0000313|EMBL:AAM72146.1, ECO:0000313|Proteomes:UP000001007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49652 / DSM 12025 / NBRC 103806 / TLS
RC   {ECO:0000313|Proteomes:UP000001007};
RX   PubMed=12093901; DOI=10.1073/pnas.132181499;
RA   Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J.,
RA   Deboy R., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D.,
RA   Durkin A.S., Kolonay J.L., Yang F., Holt I., Umayam L.A., Mason T.,
RA   Brenner M., Shea T.P., Parksey D., Nierman W.C., Feldblyum T.V.,
RA   Hansen C.L., Craven M.B., Radune D., Vamathevan J., Khouri H., White O.,
RA   Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A.,
RA   Fraser C.M.;
RT   "The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic,
RT   anaerobic, green-sulfur bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006470; AAM72146.1; -; Genomic_DNA.
DR   RefSeq; NP_661804.1; NC_002932.3.
DR   RefSeq; WP_010932591.1; NC_002932.3.
DR   AlphaFoldDB; Q8KDY3; -.
DR   STRING; 194439.CT0911; -.
DR   REBASE; 6236; CteTORF908P.
DR   EnsemblBacteria; AAM72146; AAM72146; CT0911.
DR   KEGG; cte:CT0911; -.
DR   PATRIC; fig|194439.7.peg.824; -.
DR   eggNOG; COG3587; Bacteria.
DR   HOGENOM; CLU_011799_0_0_10; -.
DR   OrthoDB; 9804145at2; -.
DR   Proteomes; UP000001007; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0015668; F:type III site-specific deoxyribonuclease activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR045572; RE_endonuc_C.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF19778; RE_endonuc; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|EMBL:AAM72146.1};
KW   Hydrolase {ECO:0000313|EMBL:AAM72146.1};
KW   Nuclease {ECO:0000313|EMBL:AAM72146.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001007}.
FT   DOMAIN          88..250
FT                   /note="Helicase/UvrB N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04851"
FT   DOMAIN          875..971
FT                   /note="Type III restriction enzyme C-terminal endonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF19778"
SQ   SEQUENCE   991 AA;  112131 MW;  041460F913E04447 CRC64;
     MKLHFEPNLD YQLQAIEAVC DLFRGQEICR TEFTVTRQTS LAFAKSDPGV GDLGVGNRLT
     LLDDEILANL RDVQIRNGLA PSETLASGDF TVEMETGTGK TYVYLRTIFE LNKRYGFTKF
     VIVVPSVAIK EGVYKSLQIT EEHFKSLYAG VPFDYFLYDS AKLGQVRSFA TGANIQIMVV
     TVGAINKKDV NNLYKDSEKT GGEKPIDLIR ATRPIVIVDE PQSVDGGLQG QGKAALDAMN
     PLCTLRYSAT HVDKHHMVYR LDAVDAYEKR LVKQIEVASA TVEDAHNKPY VRLVSVSNKK
     GTISARVELD MQTAGGKVRR QEVTVQDGDN LEQTTGRAMY ANCRIGEIRV AKGDEYLELR
     VPGGELYLKP GQAWGDVDAL AVQREMIRRT IREHLDKEKR LRPQGIKVLS LFFIDEVAKY
     RSYDVDGNPV KGDYARIFEE EYRRAANLPG YRTLFQEVDL TRAAEEVHNG YFSIDKKGGW
     TDTAENNASN RENAERAYNL IMKEKEKLLS LDTPLKFIFS HSALKEGWDN PNVFQICTLR
     DIQTERERRQ TIGRGLRLCV NQQGERVRGF EVNTLTVVAM ESYEQFAENL QKEIEEDTGI
     RFGVVEQHQF AGIPVSQPDG STVPLGVEQS RALWEHLKTA GYIDDKGKVQ DSLKQALKDD
     TLVVPEPFAA QRDQIVAGLK KLAGRLEIRN ADERRQVRTR QAVLHSPEFK ALWERIKYKS
     TYRVHFDNKK LIKRCIRAVQ EAPAIPKTRL QWRKADIAIG KAGVEATERE GAATVVIDEA
     DIELPDLLTE LQDRTQLTRR SIQRILSGSG RLKDFKRNPQ AFIELTAEAI NRCKRLAVVD
     GIKYQRLGNE HYYAQELFEQ EELTGYLRNL LDANKGVYEQ IVYDSDTERT FGDQLEKNDA
     IKVYAKLPGW FTVPTPLGSY NPDWAVLVEK DGAERLYFVV ETKSGLFAED LREKERAKIE
     CGKAHFKALE VGEAPARFVM ARTVDEVLAD P
//