ID   Q8KE56_CHLTE            Unreviewed;       627 AA.
AC   Q8KE56;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   SubName: Full=Oxaloacetate decarboxylase, alpha subunit {ECO:0000313|EMBL:AAM72070.1};
DE            EC=4.1.1.3 {ECO:0000313|EMBL:AAM72070.1};
GN   Name=oadA {ECO:0000313|EMBL:AAM72070.1};
GN   OrderedLocusNames=CT0834 {ECO:0000313|EMBL:AAM72070.1};
OS   Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
OS   (Chlorobium tepidum).
OC   Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC   Chlorobaculum.
OX   NCBI_TaxID=194439 {ECO:0000313|EMBL:AAM72070.1, ECO:0000313|Proteomes:UP000001007};
RN   [1] {ECO:0000313|EMBL:AAM72070.1, ECO:0000313|Proteomes:UP000001007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49652 / DSM 12025 / NBRC 103806 / TLS
RC   {ECO:0000313|Proteomes:UP000001007};
RX   PubMed=12093901; DOI=10.1073/pnas.132181499;
RA   Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J.,
RA   Deboy R., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D.,
RA   Durkin A.S., Kolonay J.L., Yang F., Holt I., Umayam L.A., Mason T.,
RA   Brenner M., Shea T.P., Parksey D., Nierman W.C., Feldblyum T.V.,
RA   Hansen C.L., Craven M.B., Radune D., Vamathevan J., Khouri H., White O.,
RA   Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A.,
RA   Fraser C.M.;
RT   "The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic,
RT   anaerobic, green-sulfur bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
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DR   EMBL; AE006470; AAM72070.1; -; Genomic_DNA.
DR   RefSeq; NP_661728.1; NC_002932.3.
DR   RefSeq; WP_010932515.1; NC_002932.3.
DR   AlphaFoldDB; Q8KE56; -.
DR   STRING; 194439.CT0834; -.
DR   EnsemblBacteria; AAM72070; AAM72070; CT0834.
DR   KEGG; cte:CT0834; -.
DR   PATRIC; fig|194439.7.peg.758; -.
DR   eggNOG; COG0511; Bacteria.
DR   eggNOG; COG5016; Bacteria.
DR   HOGENOM; CLU_000395_4_3_10; -.
DR   OrthoDB; 9807469at2; -.
DR   Proteomes; UP000001007; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   CDD; cd06850; biotinyl_domain; 1.
DR   CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001882; Biotin_BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR003379; Carboxylase_cons_dom.
DR   InterPro; IPR000891; PYR_CT.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   Pfam; PF02436; PYC_OADA; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
DR   PROSITE; PS00188; BIOTIN; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   4: Predicted;
KW   Biotin {ECO:0000256|ARBA:ARBA00023267};
KW   Lyase {ECO:0000313|EMBL:AAM72070.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001007}.
FT   DOMAIN          4..276
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
FT   DOMAIN          557..627
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50968"
SQ   SEQUENCE   627 AA;  68430 MW;  A8658C7B5FB75A13 CRC64;
     MKKIRFMDVS FRDGFQSCYG ARVKTEDFLP VLEAAVEAGT DNFEIGGGAR FQSLYFYCQE
     DAFEMMDACR RVVGPDINLQ TLSRGANVVG LVSQSRDIID LHAKMFKKHG VSTIRNFDAL
     MDVRNLAWSG QCIVNAGLKH QVVIALMGLP PGLNEPYCHT PQFYLDKLKE ILDAGIPFDS
     VAFKDASGTT TPAVIYETIK GARKMLPEGT VLQFHTHDTA GMGVACNFAA IEAGIDIIDL
     AMAPVSGGTA EVDILTMWHR LRGTDYTLDI DQEKYLEVER MFIEHMDKYY MPPEAKEVNP
     VIPFSPMPGG ALTANTQMMR DHGTLHFFPE VIRNMREVVA KGGFGSSVTP VSQFYFQQAF
     ANTVQGPWKK IVDGYGKMVL GYFGKTPAAP DPEVVALASE QLGLEPTVQD VHDINDRNPD
     LGIEHNRKLL EEAGLPVTDE NIFIAATCGA KGISFLKGDK PMGIRYKADV EAEEKAKHSE
     EELKVTSHGN SLQDRLSDLI KPAGRSNLSG NYMVMVDGKS FNVVIADGMV MAQSIASGAQ
     PFVMPVPTAV SAPQQHRGTP VMPSMPGNVF KMEVEAGQKV EEGQEVAVME AMKMESPVKA
     PKSGIVTVVL AKPGDAVSAA QALMYIE
//