ID Q8KIL9_RHIEC Unreviewed; 375 AA.
AC Q8KIL9;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 151.
DE SubName: Full=Alcohol dehydrogenase protein {ECO:0000313|EMBL:AAM54942.1};
DE EC=1.1.1.1 {ECO:0000313|EMBL:AAM54942.1};
GN OrderedLocusNames=RHE_PD00107 {ECO:0000313|EMBL:AAM54942.1};
OS Rhizobium etli (strain CFN 42 / ATCC 51251).
OG Plasmid sym p42d {ECO:0000313|Proteomes:UP000001936}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=347834 {ECO:0000313|EMBL:AAM54942.1, ECO:0000313|Proteomes:UP000001936};
RN [1] {ECO:0000313|Proteomes:UP000001936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX PubMed=12801410; DOI=10.1186/gb-2003-4-6-r36;
RA Gonzalez V., Bustos P., Ramirez-Romero M.A., Medrano-Soto A., Salgado H.,
RA Hernandez-Gonzalez I., Hernandez-Celis J.C., Quintero V.,
RA Moreno-Hagelsieb G., Girard L., Rodriguez O., Flores M., Cevallos M.A.,
RA Collado-Vides J., Romero D., Davila G.;
RT "The mosaic structure of the symbiotic plasmid of Rhizobium etli CFN42 and
RT its relation to other symbiotic genome compartments.";
RL Genome Biol. 4:R36.1-R36.13(2003).
RN [2] {ECO:0000313|Proteomes:UP000001936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT seven interacting replicons.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; U80928; AAM54942.1; -; Genomic_DNA.
DR RefSeq; WP_004673287.1; NC_004041.2.
DR AlphaFoldDB; Q8KIL9; -.
DR GeneID; 45960457; -.
DR KEGG; ret:RHE_PD00107; -.
DR HOGENOM; CLU_026673_14_1_5; -.
DR OrthoDB; 9770544at2; -.
DR Proteomes; UP000001936; Plasmid sym p42d.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08281; liver_ADH_like1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AAM54942.1}; Plasmid {ECO:0000313|EMBL:AAM54942.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001936};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 18..373
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 375 AA; 39112 MW; B1B68DE8305B3FBD CRC64;
MQMRSVILRE SGLPKPYSNS KPLKIELVEL TPPGPMEVLV KIKAAGVCHS DLSAINGDRP
RPLPVALGHE ASGVVAAIGP SVEKVEVGDH VVMSFLPVCG HCSYCAEGRA SLCEPGYQAN
AAGTLLSGGK HIRLRGYEIN HHSGVSAFSE YAVVSASSVV KVTKDIDLAT AALFGCAVMT
GVGAVMNTCG VRPGRSVAVI GLGGVGLSAI LGAVASGASD IVAIDLIQAK LDLAKELGAT
KTFLATSPNI VAQVKGATSG GVDYAIEMAG SKKAFELAYE ITRRGGMTAT AGLASANSRF
EVSPLPLVGE ERTIKGSYMG SCVPSRDIPR YIDLYLKGKL PVDKLLSSTG PLDEINEVFD
RLDRAEINRH LVLMD
//
