ID Q8KRA5_9STRE Unreviewed; 145 AA.
AC Q8KRA5;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=Ligase VanB2 {ECO:0000313|EMBL:AAL07283.1};
DE Flags: Fragment;
GN Name=vanB2 {ECO:0000313|EMBL:AAL07283.1};
OS Streptococcus lutetiensis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=150055 {ECO:0000313|EMBL:AAL07283.1};
RN [1] {ECO:0000313|EMBL:AAL07283.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=5-F9 {ECO:0000313|EMBL:AAL07283.1};
RX PubMed=12878522; DOI=10.1128/AAC.47.8.2579-2583.2003;
RA Dahl K.H., Sundsfjord A.;
RT "Transferable vanB2 Tn5382-containing elements in fecal streptococcal
RT strains from veal calves.";
RL Antimicrob. Agents Chemother. 47:2579-2583(2003).
CC -!- SIMILARITY: Belongs to the D-alanine--D-alanine ligase family.
CC {ECO:0000256|ARBA:ARBA00010871}.
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DR EMBL; AY035703; AAL07283.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8KRA5; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR011095; Dala_Dala_lig_C.
DR PANTHER; PTHR23132; D-ALANINE--D-ALANINE LIGASE; 1.
DR PANTHER; PTHR23132:SF25; D-ALANINE--D-ALANINE LIGASE A; 1.
DR Pfam; PF07478; Dala_Dala_lig_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AAL07283.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409}.
FT DOMAIN 6..81
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAL07283.1"
FT NON_TER 145
FT /evidence="ECO:0000313|EMBL:AAL07283.1"
SQ SEQUENCE 145 AA; 15544 MW; 258D1CB1DFE6E484 CRC64;
DKSLAYILTK NAGIAVPEFQ MIDKGDKPEA GALTYPVFVK PARSGSSFGV TKVNGTEELN
AAIEAAGQYD GKILIEQAIS GCEVGCAVMG NEDDLIVGEV DQIRLSHGIF RIHQENEPEK
GSENAMITVP ADIPVEERNR VQETA
//
