ID   Q8NFV0_HUMAN            Unreviewed;        55 AA.
AC   Q8NFV0;
DT   01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2002, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Hair-specific type II keratin protein {ECO:0000313|EMBL:AAN04664.1};
DE   Flags: Fragment;
GN   Name=KRTHB6 {ECO:0000313|EMBL:AAN04664.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAN04664.1};
RN   [1] {ECO:0000313|EMBL:AAN04664.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Bairwa N.K., Bamezai R.;
RT   "Mutation Analysis of Helix Termination Motif Region of hHb6 Gene in Two
RT   Unrelated Monilethrix Families of Indian Origin.";
RL   Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF416706; AAN04664.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8NFV0; -.
DR   PeptideAtlas; Q8NFV0; -.
DR   ChiTaRS; KRT86; human.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.170; -; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45616:SF52; KERATIN, TYPE II CUTICULAR HB6; 1.
DR   Pfam; PF00038; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685};
KW   Keratin {ECO:0000256|ARBA:ARBA00022744, ECO:0000313|EMBL:AAN04664.1}.
FT   DOMAIN          1..55
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   COILED          1..35
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAN04664.1"
FT   NON_TER         55
FT                   /evidence="ECO:0000313|EMBL:AAN04664.1"
SQ   SEQUENCE   55 AA;  6284 MW;  1769200B920DB828 CRC64;
     LSDARCKLAE LEGALQKAKQ DMACLIREYQ EVMNSKLGLD IEIATYRRLL EGKEQ
//