ID Q8P556_XANCP Unreviewed; 390 AA.
AC Q8P556;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:AAM42759.1};
GN OrderedLocusNames=XCC3489 {ECO:0000313|EMBL:AAM42759.1};
OS Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB
OS 528 / LMG 568 / P 25).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=190485 {ECO:0000313|EMBL:AAM42759.1, ECO:0000313|Proteomes:UP000001010};
RN [1] {ECO:0000313|EMBL:AAM42759.1, ECO:0000313|Proteomes:UP000001010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25
RC {ECO:0000313|Proteomes:UP000001010};
RX PubMed=12024217; DOI=10.1038/417459a;
RA da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R.,
RA Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F.Jr.,
RA Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G.,
RA Cannavan F., Cardozo J., Chambergo F., Ciapina L.P., Cicarelli R.M.B.,
RA Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B.,
RA Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F.,
RA Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T.,
RA Leite R.P.Jr., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A.,
RA Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J.,
RA Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M.,
RA Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A.Jr., Rossi A.,
RA Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A.,
RA Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M.,
RA Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P.;
RT "Comparison of the genomes of two Xanthomonas pathogens with differing host
RT specificities.";
RL Nature 417:459-463(2002).
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DR EMBL; AE008922; AAM42759.1; -; Genomic_DNA.
DR RefSeq; NP_638835.2; NC_003902.1.
DR AlphaFoldDB; Q8P556; -.
DR STRING; 190485.XCC3489; -.
DR EnsemblBacteria; AAM42759; AAM42759; XCC3489.
DR KEGG; xcc:XCC3489; -.
DR PATRIC; fig|190485.4.peg.3732; -.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_018816_15_1_6; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000001010; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF24; MULTIDRUG RESISTANCE EFFLUX PUMP; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR PRINTS; PR01490; RTXTOXIND.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001010};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 90..334
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 131..165
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 204..252
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 390 AA; 41938 MW; 61C7B3FE4405A4E6 CRC64;
MDSLRAGVAP LSAPAGCPLS FCSDCAPMNT PADTAPTAAQ RRRRRRRRLY GVLGFGGLAL
IGVALVLYAW RLPPFTSAVE RTENAMVHGQ VTVIAPQVSG YVTQVPVQDF AHVRRGQLLA
KIDDRIYAQH LEQAKAQLQT TQANLANWEQ QRHSAEATIA EQRATLSSNQ AQRDRTRSAY
ARAQQLANQK LVSEQDRDTA FAARAQADAG VAQARAAVQA AEENARSVTV NRAALEAAVA
NAQAAVQLAQ INLDNTRILA PRDGQLGQLG VRQGAYVTNG TQLMALVPDT LWVVANFKET
QMANVRVGQR ASFTVDALAN ARLQGRVQEI SPAAGSEFSV LRADNATGNF VKIAQRIPLR
ISVDPGQPQA ARLRPGMSVV VAIDTAQRAE
//
