ID Q8PWL8_METMA Unreviewed; 584 AA.
AC Q8PWL8;
DT 01-OCT-2002, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2002, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Molybdenum formylmethanofuran dehydrogenase subunit {ECO:0000313|EMBL:AAM31262.1};
DE EC=1.2.99.5 {ECO:0000313|EMBL:AAM31262.1};
GN Name=fmdA {ECO:0000313|EMBL:AAM31262.1};
GN OrderedLocusNames=MM_1566 {ECO:0000313|EMBL:AAM31262.1};
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952 {ECO:0000313|EMBL:AAM31262.1, ECO:0000313|Proteomes:UP000000595};
RN [1] {ECO:0000313|EMBL:AAM31262.1, ECO:0000313|Proteomes:UP000000595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88
RC {ECO:0000313|Proteomes:UP000000595};
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baumer S., Jacobi C.,
RA Bruggemann H., Lienard T., Christmann A., Bomeke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.P., Gunsalus R.P.,
RA Fritz H.J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
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DR EMBL; AE008384; AAM31262.1; -; Genomic_DNA.
DR RefSeq; WP_011033512.1; NC_003901.1.
DR AlphaFoldDB; Q8PWL8; -.
DR GeneID; 82160617; -.
DR KEGG; mma:MM_1566; -.
DR PATRIC; fig|192952.21.peg.1811; -.
DR eggNOG; arCOG04461; Archaea.
DR HOGENOM; CLU_035587_0_0_2; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd01304; FMDH_A; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR013108; Amidohydro_3.
DR InterPro; IPR012027; Formylmethanofuran_DH_asu.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR03121; one_C_dehyd_A; 1.
DR PANTHER; PTHR11647:SF99; D-PHENYLHYDANTOINASE-RELATED; 1.
DR PANTHER; PTHR11647; HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER; 1.
DR Pfam; PF07969; Amidohydro_3; 1.
DR PIRSF; PIRSF006453; FwdA; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 2.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:AAM31262.1}.
FT DOMAIN 46..519
FT /note="Amidohydrolase 3"
FT /evidence="ECO:0000259|Pfam:PF07969"
SQ SEQUENCE 584 AA; 65094 MW; 8DEF9FC2CA6C1E6A CRC64;
MAGTIAIKNG YVFDPLNEIN GEKMDIFIRD GKVVKELSAS EMKTSRVIDA SGMTVMPGGV
DSHSHVAGAK VNAGRSMRPE DHYKANLKKT PLTHSGSGYT VPSVYKQGYD YAAMGYTTVF
EAAVPPLEAR HTHEEMRATP LLDMGGYLVL GNNFFLMRYL RDGDMEKAAA YVAWMMKTHK
TYGIKCVNPA GVENWAWGKN VSTLDETNIH FEITPREVIK GLTEVNETLG MPMPVHLHAN
NLGHPGCYAI TKDSLKIPDG VKTKQNMAVE WAETKMDLSR DRSVYLTHLM FNSFAGTTWG
DCESGVKDIA DYINNKDHVV IDSGCTPFGE ATVMTGDGPA IHDLYTLTGN KWSNTDVEME
CGSGVLPFTY LKSNPVHSLQ WAMGLECLLL IKDPWKTIMT TDSPNGGPFT KYPEVMTWIM
SEAFRKQTFS ECHKWANDRS ELGGINRELS LYDLAILTRA NPAKTIGMAH RKGSLGVGAD
GDVTVYNINP QQLDANNYEA LLRTFRKAEY TVKGGEIVAV KGEIVSLPEK RTYYSEVHVE
NEREKEMLVD VKEWFRYYTL GFANYSTPEK YLANPTPIQV NSER
//
